Congenital merosin-deficient muscular dystrophy 1A
MONDO:0011925Congenital muscular dystrophy type 1A (MCD1A) belongs to a group of neuromuscular disorders with onset at birth or infancy characterized by hypotonia, muscle weakness and muscle wasting.
Also known as: CMD1A, LAMA2 congenital muscular dystrophy, MDC1A, congenital merosin-deficient muscular dystrophy type 1A, congenital muscular dystrophy caused by mutation in LAMA2, congenital muscular dystrophy due to laminin alpha2 deficiency, merosin-deficient congenital muscular dystrophy type 1A, merosin-negative congenital muscular dystrophy
8 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Mind-Controlled tablets: brain implant trial aims to give voice to the paralyzed
Disease control Recruiting nowThis early-stage trial tests a brain-computer interface called BrainGate for people with paralysis from conditions like ALS or spinal cord injury. A small sensor is placed in the brain to interpret movement-related signals, allowing users to control a tablet computer just by thin…
Phase: NA • Sponsor: Leigh R. Hochberg, MD, PhD. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
-
New handheld scanner could replace MRI for muscle disease monitoring
Diagnosis Recruiting nowThis study is testing a handheld device called mScan that uses a tiny, painless electrical current to measure muscle health. Researchers want to see if it can give similar results to an MRI, but faster and more conveniently. The study involves 150 adults with and without muscle d…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:03 UTC
-
Virtual park cycling could slow muscle decline in children
Symptom relief Recruiting nowThis study tests whether cycling while using a virtual park app can slow the loss of motor function in children and teens with neuromuscular diseases like muscular dystrophy. Twenty-two participants will first receive standard care for 3 months, then use the virtual park bike 3 t…
Phase: NA • Sponsor: Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
-
A protein clue in the fight against muscular dystrophy?
Knowledge-focused Recruiting nowThis study looks at whether levels of a protein called HMGB1 are different in people with LAMA2-related muscular dystrophy, a condition that causes severe muscle weakness. Researchers will measure HMGB1 in blood and muscle samples already collected from about 25 patients. The goa…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
-
Massive study seeks answers for rare inherited nerve diseases
Knowledge-focused Recruiting nowThis study aims to learn more about rare inherited disorders that affect the brain, spinal cord, muscles, and nerves. Researchers will collect medical history, perform exams, and run genetic tests on up to 3,500 participants. No new treatments are tested; the goal is to better un…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
-
New study tracks toddlers with rare muscle disease to prep for future treatments
Knowledge-focused Recruiting nowThis study watches how children under 5 with LAMA2-related muscular dystrophy move and develop over two years. Researchers will test muscle function, swallowing, breathing, and collect blood samples. The goal is to learn more about the disease so future treatments can be tested e…
Sponsor: Nationwide Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
-
Wearable tech tracks fatigue in muscle disease patients
Knowledge-focused Recruiting nowThis study aims to find better ways to measure fatigue and walking problems in people with neuromuscular diseases like muscular dystrophy and spinal muscular atrophy. Researchers will use a wearable sensor to track physical activity for one week in daily life and during a walking…
Sponsor: IRCCS Eugenio Medea • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
-
Swiss launch major registry to track rare muscle diseases
Knowledge-focused Recruiting nowThis study is a registry that collects health information from people in Switzerland who have neuromuscular disorders like SMA, DMD, BMD, and others. It aims to track symptoms, treatments, and outcomes over time to help researchers and doctors improve care. No new treatments are …
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC