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Commissural facial cleft

MONDO:0013300

Greatly exaggerated width of the mouth, resulting from failure of union of the maxillary and mandibular processes, with extension of the oral orifice toward the ear. The defect may be unilateral or bilateral. (Dorland, 27th ed)

Also known as: macrostomia, commissural cleft, isolated, lateral cleft, isolated, macrostomia, isolated, transverse cleft, isolated

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Musculoskeletal system disorder (207) Bone disorder (51) Human disease (14) Developmental defect during embryogenesis (8) Disorder of facial skeleton (4) Skeletal system disorder (4) Skull disorder (1) Disease by body system or component (0) Disease by developmental or physiological process (0)
Not yet recruiting 1 Completed 1
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  • Heart valve positioning study aims to prevent artery blockage

    Knowledge-focused Not yet recruiting

    This study compares two established techniques for placing a TAVI heart valve to see which one better aligns the valve with the patient's own valve openings, reducing the risk of blocking coronary arteries. Forty patients with severe aortic stenosis will be randomly assigned to o…

    Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused

    Last updated Jun 27, 2026 07:54 UTC

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