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Commissural facial cleft

MONDO:0013300

Greatly exaggerated width of the mouth, resulting from failure of union of the maxillary and mandibular processes, with extension of the oral orifice toward the ear. The defect may be unilateral or bilateral. (Dorland, 27th ed)

Also known as: macrostomia, commissural cleft, isolated, lateral cleft, isolated, macrostomia, isolated, transverse cleft, isolated

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Musculoskeletal system disorder (207) Bone disorder (51) Human disease (14) Developmental defect during embryogenesis (8) Disorder of facial skeleton (4) Skeletal system disorder (4) Skull disorder (1) Disease by body system or component (0) Disease by developmental or physiological process (0)
Not yet recruiting 1 Completed 1
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  • Jaw implants aim to boost life quality after surgery

    Symptom relief Completed

    This study looked at how well Global D implants work for orthognathic (jaw) surgery and whether they improve patients' quality of life. 198 people who had their first jaw surgery received these implants. Researchers measured quality of life before and after surgery using a specia…

    Sponsor: Global D • Aim: Symptom relief

    Last updated Jun 27, 2026 08:11 UTC

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