Colchicine poisoning
MONDO:0017859A potentially life-threatening poisoning, due to ingestion of the drug or consumption of the plant Colchicum autumnale, that usually begins with gastrointestinal symptoms (e.g. abdominal pain, nausea, vomiting, and diarrhea, that cause severe dehydration) and an initial leukocytosis leading to marrow failure (24 hours after ingestion), followed by potentially fatal multi-organ failure with mental status change, oliguric renal failure, disseminated intravascular coagulation, electrolyte imbalance, acid-base disturbance, cardiac failure/arrest and shock within 1-3 days.
10 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Heart attack survivors with gene variant may benefit from colchicine
Disease control Recruiting nowThis pilot study tests whether the drug colchicine can reduce artery plaque in 120 heart attack survivors who have a specific genetic change (TET2-CHIP). Participants take colchicine or standard care for 12 months. The goal is to see if this genetic marker can guide personalized …
Phase: PHASE4 • Sponsor: Shenyang Northern Hospital • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
-
Can a common gout pill protect heart bypass patients?
Disease control Recruiting nowThis pilot study is testing whether the anti-inflammatory drug colchicine can lower inflammation and reduce the risk of atrial fibrillation (an irregular heartbeat) after coronary artery bypass surgery. 24 adults scheduled for bypass surgery will be randomly assigned to receive e…
Phase: PHASE4 • Sponsor: Ayesha Ather • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
-
Can charcoal speed up poison recovery? new study aims to find out
Disease control Recruiting nowThis pilot study is testing whether giving activated charcoal within 6 hours of swallowing a poisonous substance can prevent the poison from getting worse and shorten hospital stays. About 100 adults and children who have ingested a substance that charcoal can absorb will be rand…
Phase: PHASE4 • Sponsor: Laval University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
-
Heart bypass patients may benefit from common arthritis drug
Disease control Recruiting nowThis study tests whether taking a low dose of colchicine (a medicine used for gout) every day for a year can prevent the new blood vessels created during heart bypass surgery from failing. About 100 adults who recently had bypass surgery will take colchicine or no extra treatment…
Phase: PHASE4 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
-
Heart surgery patients get new hope: colchicine may stop Post-Op AFib
Disease control Recruiting nowThis study tests whether the anti-inflammatory drug colchicine, combined with a special surgical technique, can prevent atrial fibrillation (a type of irregular heartbeat) after coronary artery bypass surgery. Researchers will compare 70 patients receiving colchicine plus the new…
Phase: PHASE4 • Sponsor: Tomsk Cardiology Research Institute • Aim: Disease control
Last updated Jun 26, 2026 14:24 UTC