Can a common gout pill protect heart bypass patients?

NCT ID NCT07287345

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing whether the anti-inflammatory drug colchicine can lower inflammation and reduce the risk of atrial fibrillation (an irregular heartbeat) after coronary artery bypass surgery. 24 adults scheduled for bypass surgery will be randomly assigned to receive either colchicine or a placebo, starting 5 days before surgery and continuing for 10 days after. Researchers will measure inflammatory markers and track who develops atrial fibrillation, aiming to gather data for a larger future trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

colchicine

What this could lead to

If it works, this could point toward a simple, low-cost way to prevent a common complication of heart bypass surgery.

What could go wrong

This is a very small pilot study with only 24 participants, so results may not apply to everyone. Colchicine can cause side effects like stomach upset or, rarely, more serious issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colchicine poisoning coronary artery disorder atrial fibrillation prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Kentucy

    RECRUITING

    Lexington, Kentucky, 40536, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••