Colchicine poisoning
MONDO:0017859A potentially life-threatening poisoning, due to ingestion of the drug or consumption of the plant Colchicum autumnale, that usually begins with gastrointestinal symptoms (e.g. abdominal pain, nausea, vomiting, and diarrhea, that cause severe dehydration) and an initial leukocytosis leading to marrow failure (24 hours after ingestion), followed by potentially fatal multi-organ failure with mental status change, oliguric renal failure, disseminated intravascular coagulation, electrolyte imbalance, acid-base disturbance, cardiac failure/arrest and shock within 1-3 days.
10 clinical trials for this condition and its sub-types.
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Could a cheap arthritis drug cut stroke survivors' heart risks?
Disease control Not yet recruitingThis study tests whether a low-dose anti-inflammatory drug called colchicine can help people who have had a brain hemorrhage (a type of stroke) recover better and avoid future heart attacks or strokes. About 1,125 adults with signs of artery disease will take either colchicine or…
Phase: PHASE3 • Sponsor: Population Health Research Institute • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Cheap arthritis drug may keep bypass grafts working longer
Prevention Not yet recruitingThis study tests whether taking a low dose of colchicine (0.5 mg) every day for two years after coronary artery bypass grafting (CABG) can prevent the new blood vessel grafts from failing. About 622 adults who just had bypass surgery will be randomly assigned to get either colchi…
Phase: NA • Sponsor: Beijing Anzhen Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:29 UTC