Cleft lip/palate
MONDO:0016044Cleft lip and palate is a fissure type embryopathy extending across the upper lip, nasal base, alveolar ridge and the hard and soft palate.
Also known as: FLP, alveolar cleft lip and palate, cleft lip and palate, cleft lip-alveolus-palate syndrome
29 clinical trials for this condition and its sub-types.
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Broader categories
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New speech therapy approach may help children with cleft palate speak more clearly
Disease control ENROLLING_BY_INVITATIONThis trial compares two speech therapy approaches for Cantonese-speaking children and teens aged 4 to 17 who have cleft palate with or without cleft lip. One method focuses on practicing individual sounds, while the other targets the overall sound system. The goal is to see which…
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Smart toothbrush trial for cleft surgery kids pulled before it started
Symptom relief TerminatedThis study aimed to see if using a connected toothbrush (Ara® KOLIBREE) for one month before alveolar bone graft surgery could improve oral hygiene in children aged 5 to 12 with cleft lip and palate. The trial was withdrawn before enrolling any participants, so no results are ava…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Which expander works best for cleft kids? new trial aims to find out
Knowledge-focused OngoingThis study compares two dental devices—the quadhelix and mini-hyrax expanders—in 24 children with cleft lip and palate who need their upper jaw widened before bone graft surgery. Researchers will use 3D scans and models to measure how much the jaw expands. The goal is to see whic…
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Cleft care network aims to boost outcomes by sharing data
Knowledge-focused ENROLLING_BY_INVITATIONThis study brings together medical teams that treat children with cleft lip and/or palate. They will collect information on speech, hearing, dental health, and quality of life from about 1,000 patients. The goal is to compare results across centers and find ways to improve care. …
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC