Cleft lip/palate

This study compares a new stem-cell-based kit to the standard bone graft surgery for repairing gaps in the upper jaw (alveolar cleft) in children aged 6 to 11 with cleft lip and palate. The kit uses stem cells from baby teeth combined with a special material to help bone grow. Th…

This study tests whether teaching speech and language skills to infants with unrepaired cleft palate can improve their communication before palate repair surgery. Two hundred infants aged 6 to 10 months will join weekly coaching sessions with their families. The goal is to see if…

This study looks at different presurgical treatments for infants born with cleft lip and palate. These treatments help shape the mouth and nose before surgery. Researchers will compare how well each approach works, how many clinic visits are needed, and how much burden it places …

This study will use MRI scans to see how well the palate and throat muscles work after a special surgery for cleft palate repair. The surgery uses a piece of cheek muscle to close the gap and aims to improve speech. Ten people who have not had early treatment will get the surgery…