Central nervous system primitive neuroectodermal neoplasm
MONDO:0000640A neuroectodermal tumor that involves the central nervous system.
Also known as: CNS PNET, CNS primitive neuroectodermal neoplasm, CNS primitive neuroectodermal tumor, CNS primitive neuroectodermal tumour, central nervous system PNET, central nervous system neuroectodermal tumor, central nervous system neuroectodermal tumour, central nervous system primitive neuroectodermal neoplasm
2790 clinical trials for this condition and its sub-types, 8 tagged with Central nervous system primitive neuroectodermal neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Central nervous system primitive neuroectodermal neoplasm
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Intracranial primitive neuroectodermal tumor 0 trials · 8 incl. sub-types
4 sub-types
- Cerebral neuroblastoma 4 trials Sub-types →
- Olfactory neuroblastoma 4 trials Sub-types →
- Pediatric cerebral ependymoblastoma 0 trials Sub-types →
- Pediatric infratentorial ependymoblastoma 0 trials
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2 sub-types
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Ependymoblastoma 5 trials
3 sub-types
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Ganglioneuroma 5 trials
1 sub-type
- Cutaneous ganglioneuroma 0 trials
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1 sub-type
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Spinal cord neuroblastoma 0 trials
Most studied deeper sub-types
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Immune cells engineered to hunt brain tumors in kids
Disease control Recruiting nowThis early-phase trial tests a new treatment for children and young adults with medulloblastoma or similar brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to recognize and attack tumor cells, deliv…
Phase 1 • Sponsor: Stanford University • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Engineered t cells take on deadly brain cancers
Disease control Recruiting nowThis early-phase trial tests a new type of immune therapy for people with certain aggressive brain tumors, including DIPG and high-grade glioma. The treatment uses the patient's own T cells, which are modified in the lab to recognize a protein called GD2 on cancer cells and to pr…
Phase 1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New hope for toddlers with aggressive brain cancer: experimental spinal-fluid chemo
Disease control Recruiting nowThis early-phase study tests whether adding chemotherapy directly into the spinal fluid (intrathecal topotecan) followed by maintenance pills is feasible for children under 6 with high-risk embryonal brain tumors. About 15 children will receive this treatment after standard high-…
Early phase 1 • Sponsor: C17 Council • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Targeted radiation zaps childhood brain tumors in early trial
Disease control Recruiting nowThis phase 1 trial tests a drug called 177Lu-DTPA-omburtamab, which delivers radiation directly to tumor cells in children and teens with recurrent or refractory medulloblastoma or other central nervous system (CNS) tumors that have spread. The drug targets a protein called B7-H3…
Phase 1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Tailor-Made T-Cells take on childhood brain cancer
Disease control Recruiting nowThis early-stage trial tests whether personalized immune cells (T-cells) can safely treat young children with aggressive brain tumors. The T-cells are designed to attack unique markers found on each child's tumor. Up to 12 children under 5 with embryonal brain tumors or recurrent…
Phase 1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Brain tumor virus therapy tested in kids and young adults
Disease control Recruiting nowThis phase 2 trial tests whether a single injection of DNX-2401, a virus designed to kill cancer cells, can shrink or stabilize recurrent high-grade brain tumors in 39 children and young adults. Participants receive the virus directly into the tumor during a biopsy procedure. The…
Phase 2 • Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Global brain tumor registry aims to unlock secrets of rare childhood cancers
Knowledge-focused Recruiting nowThis international registry collects medical data and biological samples from children and adults with rare brain tumors like medulloblastoma and ependymoma. By gathering information from patients not in clinical trials, researchers hope to improve treatment recommendations and i…
Sponsor: Universitätsklinikum Hamburg-Eppendorf • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC