Central nervous system infectious disorder
MONDO:0024619An infectious process that affects the brain and/or spinal cord. Representative examples include encephalitis, poliomyelitis, arachnoiditis, and meningitis.
Also known as: central nervous system infectious disease, central nervous system infectious disorder, infectious disease of central nervous system, central nervous system infection, infections, central nervous system
168 clinical trials for this condition and its sub-types.
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Broader categories
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Polio Survivors' hope dashed: trial of immune treatment halted early
Disease control TerminatedThis study tested a blood product called immune globulin (Flebogamma) in 191 people with post-polio syndrome, a condition causing new muscle weakness years after polio. The goal was to see if it could improve walking distance and reduce pain. The trial was terminated early, so we…
Phase: PHASE2, PHASE3 • Sponsor: Instituto Grifols, S.A. • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Nose drops with friendly bacteria could pave way for meningitis vaccine
Knowledge-focused TerminatedThis study gave healthy adults nose drops containing a harmless bacteria (N. lactamica) to see how the body's immune system responds. The goal is to learn if the immune response is the same whether the bacteria is cleared after 4 days or 14 days. This information will help design…
Phase: NA • Sponsor: University Hospital Southampton NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Sticker shock: simple reminder may cut unnecessary IV antibiotic use
Knowledge-focused TerminatedThis study tested whether placing a reminder sticker on the charts of adult hospital patients receiving IV fluoroquinolone antibiotics would encourage doctors to switch them to oral pills sooner. The trial involved 168 patients at a single hospital in Thailand. Unfortunately, the…
Phase: NA • Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC