Catecholaminergic polymorphic ventricular tachycardia
MONDO:0017990Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a severe genetic arrhythmogenic disorder characterized by adrenergically induced ventricular tachycardia (VT) manifesting as syncope and sudden death.
Also known as: CPVT, bidirectional tachycardia induced by catecholamine, catecholaminergic polymorphic ventricular tachycardia, double tachycardia induced by catecholamines, malignant paroxysmal ventricular tachycardia, multifocal ventricular premature beats, ventricular tachycardia, catecholaminergic polymorphic, catecholamine-induced polymorphic ventricular tachycardia
40 clinical trials for this condition and its sub-types.
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New heart lead under watch: 5-Year safety check begins
Disease control ENROLLING_BY_INVITATIONThis study follows 2000 people who have or will get the OmniaSecure defibrillation lead, a wire that helps control dangerous heart rhythms. Researchers will track how often the lead causes problems over 5 years. The goal is to make sure the lead is safe and works as expected in e…
Sponsor: Medtronic • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New antibiotic pouch aims to stop infections in heart device patients
Disease control OngoingThis study is tracking 100 adults who receive an EluPro antibiotic-eluting envelope during implantation of a heart device (like a pacemaker). The envelope slowly releases antibiotics to prevent infection. Researchers are monitoring complication rates in real-world use to see how …
Sponsor: Elutia Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Heart device DiamondTemp under Real-World watch: will it deliver?
Knowledge-focused OngoingThis registry follows 545 people with arrhythmia who received a heart ablation using the DiamondTemp system. Researchers will track how many stay free of their heart rhythm problem and how many have serious side effects over 12 months. The goal is to see how well the device works…
Sponsor: Medtronic Cardiac Ablation Solutions • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Ear zaps may tweak heart rhythms, tiny study hints
Knowledge-focused OngoingThis small pilot study is testing whether a gentle, non-invasive electrical stimulation on the ear (auricular vagus nerve stimulation) can change how the heart's electrical system works. Ten people who are already scheduled for a heart procedure will receive the stimulation while…
Phase: NA • Sponsor: Northwell Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Scientists build heart cells in a dish to unravel genetic heart disease
Knowledge-focused ENROLLING_BY_INVITATIONThis study collects blood or skin samples from 100 adults with inherited heart rhythm disorders (like Long QT Syndrome or Brugada Syndrome) and healthy volunteers. Researchers will turn these samples into stem cells and then into heart cells to study how these diseases work and t…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC