Cardio-renal syndrome
MONDO:0044079A disorder of the heart and kidneys in which dysfunction of one of the organs induces dysfunction of the other organ.
Also known as: cardiorenal syndrome, Reno Cardiac syndrome, Reno-Cardiac syndrome, Reno-Cardiac syndromes, Renocardiac syndrome, Renocardiac syndromes, cardio renal syndrome, cardio-renal syndromes
38 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
New study aims to find safer heart failure treatment for kidney patients
Disease control Not yet recruitingThis study compares two drugs, finerenone and spironolactone, in 60 adults with heart failure and diabetic kidney disease who are at high risk for high potassium levels (hyperkalemia). Participants will receive either finerenone daily or spironolactone every other day, plus stand…
Phase: PHASE4 • Sponsor: Hospital de Messejana Dr. Carlos Alberto Studart Gomes • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
-
Can quick drug optimization after heart failure hospitalization save lives in women?
Disease control Not yet recruitingThis study tests whether quickly starting and increasing guideline-recommended heart failure medications after hospitalization improves outcomes in women. About 360 women from 13 Italian hospitals will be randomly assigned to either a high-intensity care group (rapid drug optimiz…
Phase: PHASE4 • Sponsor: IRCCS Policlinico S. Donato • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
-
New cooler could keep donor hearts fresher for transplant
Disease control Not yet recruitingThis study tests a new adjustable cooler for storing donor hearts during transport to the transplant hospital. The cooler aims to keep the heart at a steady temperature, reduce waste, and lower costs compared to the current standard device. About 80 adults receiving a heart trans…
Phase: NA • Sponsor: Cedars-Sinai Medical Center • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
-
Could a simple algorithm spot silent heart failure before it strikes?
Diagnosis Not yet recruitingThis study tests whether a new risk algorithm (FIND HF) can better detect undiagnosed heart failure in people at risk. About 475 adults aged 40+ will have a blood test and heart ultrasound. Researchers will compare how many high-risk vs low-risk people are found to have heart pro…
Sponsor: University of Leeds • Aim: Diagnosis
Last updated Jun 27, 2026 08:14 UTC
-
Could inflatable leg boots help heart failure patients?
Symptom relief Not yet recruitingThis study tests whether pulsatile compression boots, which rhythmically squeeze the legs, can help patients hospitalized with acute heart failure and leg swelling. The boots aim to move fluid out of the legs, improve circulation, and support heart and kidney function. One hundre…
Phase: NA • Sponsor: Odense University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
-
Heart-Kidney link under microscope in advanced heart failure study
Knowledge-focused Not yet recruitingThis study follows 100 adults with advanced heart failure for 2 years to understand how kidney function changes over time and how it relates to serious heart events like death or need for a transplant. Researchers will collect blood, urine, and stool samples, along with quality-o…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
-
Heart rate secrets: new study tracks diabetes Drug's hidden effects
Knowledge-focused Not yet recruitingThis study monitors heart rate variability in 150 adults with type 2 diabetes who also have heart failure, chronic kidney disease, or both. Participants will wear a 24-hour heart monitor before and after starting a standard SGLT2 inhibitor medication. The goal is to understand ho…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
-
New study aims to decode heart failure using body data
Knowledge-focused Not yet recruitingThis study looks at 600 people (400 with chronic heart failure and 200 healthy) to find patterns in genes, proteins, and gut bacteria that may predict who gets worse. Researchers will track patients for one year to see who is hospitalized or dies. The goal is to create a better r…
Sponsor: Xinjiang Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC