Blindness (disorder)
MONDO:0001941The lack of vision. It is caused by neurological or physiological factors.
Also known as: blindness
91 clinical trials for this condition and its sub-types, 38 tagged with Blindness (disorder) itself.
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Sub-types of Blindness (disorder)
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Cortical blindness 35 trials
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Night blindness 5 trials · 10 incl. sub-types
3 sub-types
- Congenital stationary night blindness 2 trials · 5 incl. sub-types Sub-types →
- Abnormal threshold of rods 0 trials
- Acquired night blindness 0 trials
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Amaurosis fugax 1 trial
Most studied deeper sub-types
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Surgery vs. diet: which tames diabetes better?
Disease control OngoingThis study compares two types of weight-loss surgery (gastric bypass and gastric banding) with an intensive diet and exercise program for controlling type 2 diabetes in moderately obese adults aged 25 to 55. The goal is to see which approach works best for improving diabetes and …
Sponsor: University of Pittsburgh • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Gene therapy shot could end monthly eye injections for wet AMD
Disease control OngoingThis Phase 3 trial tests a single injection of Ixo-vec gene therapy in 311 people with wet age-related macular degeneration (AMD). The goal is to see if it can maintain or improve vision as well as standard aflibercept injections, but with fewer follow-up treatments. Participants…
Phase 3 • Sponsor: Adverum Biotechnologies, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Gene therapy for wet AMD: could this mean fewer eye injections?
Disease control OngoingThis study follows 23 people with wet age-related macular degeneration who received a single dose of ADVM-022 gene therapy in an earlier trial. Researchers are checking how safe the treatment is over time and whether it continues to control the disease, potentially reducing the n…
Sponsor: Adverum Biotechnologies, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New prism device may help one-eyed pedestrians avoid collisions
Symptom relief CancelledThis study tested a prism device designed to expand the field of view for people who have lost vision in one eye. The goal was to see if the prism helps them detect pedestrians approaching from their blind side during a simulated walking task. Only one person participated before …
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Sound-Guided gaze: new device aims to sharpen eye imaging for the visually impaired
Symptom relief By invitation onlyThis study tests a device that uses real-time sound feedback to help people with vision loss fix their gaze on a target. Participants hear sounds that guide their eyes back to center when they drift. The goal is to improve the quality of eye imaging by reducing blur from eye move…
Sponsor: University Medical Center Goettingen • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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AI could turn bionic eyes into smart vision for the blind
Knowledge-focused By invitation onlyThis study tests whether AI-powered software can improve the usefulness of artificial vision for people with visual prostheses (bionic eyes). The goal is to help users better understand what they see by enhancing the visual scene, similar to augmented reality. Participants will p…
Sponsor: University of California, Santa Barbara • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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New study aims to tackle vision problems in upper manhattan
Knowledge-focused CancelledThis study aims to help adults aged 40 and older in Upper Manhattan get better eye care. It will offer free eye screenings at local health centers and senior centers, and provide support like scheduling appointments and transportation. The goal is to see if this extra help leads …
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New study aims to spot sight problems in older fall patients
Knowledge-focused OngoingThis study looks at how to better check vision in older adults (65+) who come to the hospital after a fall. Falls are common and costly, and poor eyesight can double the risk of falling again. Researchers will talk to patients, carers, and health professionals to develop a practi…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Brain zap study hopes to restore sight in the blind
Knowledge-focused OngoingThis study tests whether stimulating the visual part of the brain can create visual sensations in blind volunteers. Five adults who are blind will have a device implanted in their skull to deliver tiny electrical pulses. The goal is to learn where and how much stimulation is need…
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Free eye tests aim to catch vision loss early in harlem and washington heights
Knowledge-focused OngoingThis study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC