Gene therapy for wet AMD: Long-Term safety check underway

NCT ID NCT04645212

First seen Feb 12, 2026 · Last updated May 08, 2026 · Updated 11 times

Summary

This study follows 23 people who received a single dose of ADVM-022 gene therapy for wet age-related macular degeneration (AMD) in an earlier trial. Researchers are monitoring long-term safety and how well the treatment controls vision loss and retinal swelling over time. The goal is to see if this one-time gene therapy can reduce the need for frequent eye injections.

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Contacts and locations

Locations

  • Adverum Clinical Site

    Bakersfield, California, 93309, United States

  • Adverum Clinical Site

    Beverly Hills, California, 90211, United States

  • Adverum Clinical Site

    Lakewood, Colorado, 80228, United States

  • Adverum Clinical Site

    Deerfield Beach, Florida, 33064, United States

  • Adverum Clinical Site

    Reno, Nevada, 89502, United States

  • Adverum Clinical Site

    Philadelphia, Pennsylvania, 19107, United States

  • Adverum Clinical Site

    Nashville, Tennessee, 37203, United States

  • Adverum Clinical Site

    Bellaire, Texas, 77401, United States

  • Adverum Clinical Site

    The Woodlands, Texas, 77384, United States

Conditions

Explore the condition pages connected to this study.