Bipolar disorder

This study looked at the long-term safety of a daily drug called BHV-7000 in people with bipolar I disorder. It involved 94 participants who had completed an earlier study. The trial was terminated early, so the full safety picture is not available.

This study aimed to see how two antipsychotic drugs, aripiprazole and ziprasidone, affect heart risk in people with schizophrenia, schizoaffective disorder, or bipolar disorder. Researchers measured blood fats and heart electrical changes in 48 adults over 12 months. The trial wa…

This study tested whether adding vaccine discussions to routine behavioral health visits could reduce hesitancy and increase COVID-19 and flu shots among Latinx adults with mental illness. Clinicians used motivational interviewing and could offer a warm handoff to a nurse for vac…

This study tested whether adding a type of talk therapy (behavioral activation) to esketamine treatment helps people with depression that hasn't improved with other treatments. Six adults with major depression or bipolar disorder took part. The goal was to see if practicing new b…

This study tested a French version of a questionnaire that measures how much patients know about lithium, a drug used for bipolar and schizoaffective disorders. Researchers wanted to see if higher knowledge scores matched safe lithium levels in the blood. The study included 22 ho…

This study tested a serious game called Bipolife® for people with bipolar disorder who had already completed a psychoeducation program. The game encourages players to take their medication, keep a daily routine, and contact their doctor if symptoms return. The trial was terminate…

This study followed 167 adults with mental health issues like anxiety, depression, or sleep problems who visited their primary care doctor. Researchers used health conversations and a blood test to track lifestyle changes and heart disease risks over up to 20 years. The goal was …

This study tested a smartphone-based program to help veterans with serious mental illness (like PTSD, bipolar disorder, or schizophrenia) better recognize and describe their emotions. The goal was to see if improving emotion awareness could lower suicide risk. Only 11 veterans to…

This study aimed to find brain and movement markers in people with a type of depression that doesn't respond to standard antidepressants, called anhedonic depression. Researchers measured brain waves (P300), walking speed, and hand movements in 36 participants. The goal was to id…

This study used MRI brain scans to look at the brain's white matter connections in people with bipolar disorder. Researchers compared those whose illness responds to treatment with those who do not respond, as well as healthy volunteers. The goal was to find brain differences tha…