Brain wave test could spot stubborn depression

NCT ID NCT04456868

Terminated Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to find brain and movement markers in people with a type of depression that doesn't respond to standard antidepressants, called anhedonic depression. Researchers measured brain waves (P300), walking speed, and hand movements in 36 participants. The goal was to identify a specific pattern that could help doctors choose more effective treatments earlier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors identify a specific type of depression that doesn't respond to standard antidepressants, leading to earlier, more personalized treatment.
What could go wrong: This was a small, early-stage study that was terminated, so results are limited. The findings may not apply to all people with depression.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bipolar depression Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIPOLAR ANHEDONIC DEPRESSION

Contacts and locations

Locations

CHSR du Rouvray

Saint-Étienne-du-Rouvray, France
Rouen University Hospital

Rouen, France

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