Brain wave test could spot stubborn depression

NCT ID NCT04456868

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to find brain and movement markers in people with a type of depression that doesn't respond to standard antidepressants, called anhedonic depression. Researchers measured brain waves (P300), walking speed, and hand movements in 36 participants. The goal was to identify a specific pattern that could help doctors choose more effective treatments earlier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors identify a specific type of depression that doesn't respond to standard antidepressants, leading to earlier, more personalized treatment.

What could go wrong

This was a small, early-stage study that was terminated, so results are limited. The findings may not apply to all people with depression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bipolar depression Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHSR du Rouvray

    Saint-Étienne-du-Rouvray, France

  • Rouen University Hospital

    Rouen, France