Autosomal dominant hypocalcemia
MONDO:0018543Autosomal dominant hypocalcemia (AD hypocalcemia) is a disorder of calcium homeostasis characterized by variable degrees of hypocalcemia with abnormally low levels of parathyroid hormone (PTH) and persistent normal or elevated calciuria.
Also known as: hypocalcemia, AD hypocalcemia, hypocalcemia, autosomal dominant
12 clinical trials for this condition and its sub-types.
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Broader categories
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New hope for kids with rare calcium disease: encaleret trial launches
Disease control Recruiting nowThis study tests a drug called encaleret in 28 children (birth to 17 years) with autosomal dominant hypocalcemia type 1 (ADH1), a rare genetic condition causing low blood calcium. The goal is to see if the drug can safely raise calcium levels and reduce urinary calcium loss. Part…
Phase: PHASE2, PHASE3 • Sponsor: Calcilytix Therapeutics, Inc., a BridgeBio company • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New light probe aims to prevent thyroid surgery complication
Disease control Recruiting nowThis study tests a device called PTeye™ that uses near-infrared light to help surgeons see and protect tiny parathyroid glands during total thyroid removal. About 210 adults in Hong Kong will be randomly assigned to standard surgery or PTeye™-assisted surgery. The goal is to see …
Phase: NA • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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NIH launches major study to unlock secrets of rare bone diseases
Knowledge-focused Recruiting nowThis study aims to collect information and bone samples from up to 1,000 people with bone or mineral disorders, such as tumor-induced osteomalacia or familial tumoral calcinosis. Participants receive standard medical evaluations and may provide bone tissue from surgery or a biops…
Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused
Last updated Aug 18, 2026 06:00 UTC
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10-Year study aims to predict dangerous calcium drop after thyroid removal
Knowledge-focused Recruiting nowThis study reviews 10 years of medical records from 600 adults who had thyroid surgery at Minia University Hospital. The goal is to find out which patients are most likely to develop low calcium levels after surgery, a common complication. By identifying key risk factors, doctors…
Sponsor: Minia University • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC