Astigmatism
MONDO:0011284Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed)
Also known as: astigmatism, astigmatism (disease)
79 clinical trials for this condition and its sub-types.
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Broader categories
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Which lens implant method stays put better? a Head-to-Head test
Disease control OngoingThis study looks at whether the way a toric intraocular lens is implanted during cataract surgery affects how well it stays in place. Toric lenses correct astigmatism, but if they rotate after surgery, vision can blur. The trial compares two techniques: one using a gel-like subst…
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Aug 18, 2026 07:00 UTC
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Can a donated corneal lens correct hard-to-tract high hyperopia and astigmatism?
Disease control OngoingThis trial tests whether implanting a fresh corneal lenticule — a thin layer of donor cornea — can improve vision in people with high hyperopia (farsightedness) and high astigmatism. The lenticule is placed using a femtosecond laser, aiming to increase visual acuity and reduce as…
Phase: NA • Sponsor: Eye Hospital Pristina Kosovo • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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A donated corneal lens may fix blurry vision after a cornea transplant
Disease control OngoingThis trial tests whether implanting a fresh, donated corneal lenticule into the eye can reshape the cornea and reduce irregular astigmatism in people who have already had a full cornea transplant. The goal is to improve visual acuity and stabilize the cornea's shape. Twenty-four …
Phase: NA • Sponsor: Eye Hospital Pristina Kosovo • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Laser eye surgery showdown: which fix for nearsightedness is better?
Disease control OngoingThis study compares two common laser eye surgeries—KLEx and FS-LASIK—for treating nearsightedness and astigmatism. Researchers will follow 80 adults aged 21 and older to see which procedure provides better vision without glasses and has fewer side effects. Both surgeries reshape …
Phase: NA • Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New software may sharpen laser eye surgery for blurry vision
Disease control OngoingThis study tests a software program that predicts how much vision improvement a special laser treatment can provide for people with irregularly shaped corneas causing astigmatism. About 45 participants with vision quality issues will have their eyes treated, and the software's pr…
Phase: NA • Sponsor: London Vision Clinic • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Surfer's eye surgery may sharpen vision by reshaping cornea
Disease control ENROLLING_BY_INVITATIONThis study looks at how removing a pterygium (a fleshy growth on the eye) and replacing it with a small piece of the patient's own eye tissue changes the shape of the cornea. Researchers will measure the cornea's curve before and one month after surgery in 130 adults aged 30 to 7…
Phase: NA • Sponsor: Mughal Eye Trust Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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AI eye test: could a computer replace your eye doctor?
Diagnosis ENROLLING_BY_INVITATIONThis study compares a new AI system, called AEYE, against a human eye doctor in diagnosing keratoconus and deciding who is eligible for laser vision correction. The AI analyzes patient history, eye scans, and other data to make its recommendations. Researchers will check if the A…
Sponsor: Hazem Yassin Clinics • Aim: Diagnosis
Last updated Jun 26, 2026 17:00 UTC
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New laser surgery aims to sharpen vision for high astigmatism
Symptom relief OngoingThis study looks at how well SMILE PRO laser surgery corrects high astigmatism in people with nearsightedness. 113 patients aged 18 to 40 will have the procedure and be followed for a year to check vision sharpness, stability, and safety. The goal is to see if this advanced laser…
Phase: NA • Sponsor: Hanoi Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Laser vs. manual: which PRK method gives sharper vision?
Symptom relief OngoingThis study compares two methods of removing the outer layer of the cornea during PRK laser eye surgery. One method uses a laser to remove the layer, while the other uses a manual tool. The goal is to see which approach leads to better vision and faster healing. About 100 people a…
Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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AI predicts hidden glaucoma risk after LASIK in 10,000-Patient study
Knowledge-focused OngoingThis study uses artificial intelligence to predict true eye pressure after corneal refractive surgery like LASIK or SMILE. Standard eye pressure measurements can be falsely low after these surgeries, masking glaucoma risk. Researchers will analyze data from over 10,000 participan…
Sponsor: Tianjin Eye Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Cataract surgery tech showdown: laser vs standard handpieces
Knowledge-focused TerminatedThis study was designed to compare two newer technologies for cataract surgery: a femtosecond laser and a special handpiece that monitors eye pressure. The goal was to see if these tools cause less damage to the cornea and use less energy than standard methods. However, the study…
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC