Astigmatism
MONDO:0011284Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed)
Also known as: astigmatism, astigmatism (disease)
79 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Can a new lens design improve overnight vision correction?
Disease control Not yet recruitingThis trial evaluates Paragon CRT contact lenses with a 5mm optic zone diameter, worn overnight to temporarily reshape the cornea and correct myopia and astigmatism. Participants aged 6 to 35 will wear the lenses daily for a short period, and their comfort and visual performance w…
Phase: NA • Sponsor: CooperVision International Limited (CVIL) • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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New digital eye test in turkish put to the test
Diagnosis Not yet recruitingThis study checks if a Turkish version of the DDIVAT digital vision test gives the same results as the standard Snellen eye chart. About 200 Turkish-speaking adults, with or without glasses, will take both tests. No drugs or procedures are involved, and there are no risks.
Sponsor: Trakya University • Aim: Diagnosis
Last updated Jun 27, 2026 08:01 UTC
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New lens design aims to stop nearsightedness before it starts in children
Prevention Not yet recruitingThis trial investigates whether a new type of eyeglass lens, called a With-the-Rule Astigmatic Defocus Lens, can prevent the development of myopia (nearsightedness) in children aged 6 to 9 who have low hyperopia (farsightedness). The lens creates a 'defocus' signal around the ret…
Phase: NA • Sponsor: He Eye Hospital • Aim: Prevention
Last updated Jul 08, 2026 00:00 UTC
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Laser eye surgery showdown: which technique gives sharper vision?
Symptom relief Not yet recruitingThis trial compares two types of laser eye surgery—SMILE and ray tracing-guided LASIK—in people with nearsightedness and astigmatism. Each participant will receive one technique in one eye and the other in the other eye, allowing a direct comparison. The goal is to see which meth…
Phase: PHASE4 • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jul 25, 2026 00:00 UTC
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Could a medicated contact lens ease pain after laser eye surgery?
Symptom relief Not yet recruitingThis trial compares pain relief from bandage contact lenses soaked in the anti-inflammatory drug ketorolac versus plain lenses after photorefractive keratectomy (PRK), a type of laser eye surgery. PRK often causes significant pain in the first few days as the cornea heals. The st…
Phase: NA • Sponsor: Madina Teaching Hospital Faisalabad • Aim: Symptom relief
Last updated Jul 17, 2026 00:00 UTC
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Tailored eye incisions may cut glasses dependence after cataract surgery
Symptom relief Not yet recruitingThis study tests whether placing surgical cuts in specific parts of the cornea during cataract surgery can reduce astigmatism (blurry vision from an irregularly shaped cornea) and lower the need for glasses afterward. About 100 people with cataracts and astigmatism will be random…
Phase: NA • Sponsor: Linkoeping University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New laser aims to sharpen vision for mild nearsightedness
Symptom relief Not yet recruitingThis study tests a new excimer laser for LASIK surgery to correct mild nearsightedness (up to -1.00 diopter) with or without astigmatism. About 32 adults aged 22 and older will receive the treatment in one or both eyes. The goal is to see if the laser safely and accurately improv…
Phase: NA • Sponsor: Bausch & Lomb Incorporated • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Can the eye's stiffness predict blurry vision after cataract surgery?
Knowledge-focused Not yet recruitingThis study looks at whether the stiffness of the cornea influences how much astigmatism (blurring from an irregularly shaped cornea) develops after cataract surgery in people with pseudoexfoliation syndrome, a condition that weakens eye tissues. Researchers will measure corneal b…
Sponsor: Kata Culina • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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Could early vision screening in preschoolers prevent lifelong blindness?
Knowledge-focused Not yet recruitingThis study follows 1,000 preschool children (ages 0-6) with refractive errors like nearsightedness, farsightedness, or astigmatism. Researchers aim to map how these conditions progress, identify related health issues, and find the best ways to correct vision early. The goal is to…
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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Eye study aims to map corneal thickness in common vision problems
Knowledge-focused Not yet recruitingThis study will use a special imaging device (AS-OCT) to measure the thickness of the cornea's outer layer in 360 adults with nearsightedness, farsightedness, astigmatism, or normal vision. The goal is to see if different vision problems have unique thickness patterns. Participan…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New study aims to sharpen contact lens prescriptions for astigmatism
Knowledge-focused Not yet recruitingThis study looks at whether a new, objective way to fit toric contact lenses (for astigmatism) gives the same results as the traditional subjective method. About 45 adults with astigmatism will have their lens prescription checked both ways. The goal is to see if the new method c…
Phase: NA • Sponsor: CooperVision International Limited (CVIL) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New custom contact lenses tested for astigmatism
Knowledge-focused Not yet recruitingThis study looks at how well REVIVE samfilcon B custom toric contact lenses work for people with astigmatism. About 30 adults will wear the lenses, and eye doctors will rate their satisfaction after 14 days. The goal is to see if these lenses provide clear vision and are easy to …
Sponsor: Bausch & Lomb Incorporated • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC