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Can the eye's stiffness predict blurry vision after cataract surgery?

NCT ID NCT07722247

Knowledge-focused Sponsor: Kata Culina Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 23, 2026 · Last updated Aug 19, 2026 · Updated 3 times

Summary

This study looks at whether the stiffness of the cornea influences how much astigmatism (blurring from an irregularly shaped cornea) develops after cataract surgery in people with pseudoexfoliation syndrome, a condition that weakens eye tissues. Researchers will measure corneal biomechanics before and after surgery in 70 adults aged 50–85, comparing those with and without pseudoexfoliation. The goal is to see if preoperative corneal properties can predict surgical outcomes, which could help tailor future procedures.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If corneal stiffness is found to predict post-surgery astigmatism, surgeons may adjust their technique to improve visual outcomes for patients with pseudoexfoliation syndrome.
What could go wrong
This is an observational study, not a treatment trial, so it cannot directly improve outcomes. The findings may not apply to all types of cataract surgery or patient populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients with age-related cataract scheduled for routine phacoemulsification cataract surgery at Eye clinic Medic Jukic. Participants will include patients with pseudoexfoliation syndrome and an a control group without pseudoexfoliation syndrome of similar age range. Consecutive eligible patients who meet the inclusion criteria and provide written informed consent will be enrolled.

Ages

50 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 50-85 years * Age-related cataract scheduled for standard phacoemulsification cataract surgery with intraocular lens implantation * Presence of pseudoexfoliation syndrome (PEX group) or absence of pseudoexfoliation syndrome (control group) * Ability to provide written informed consent * Willingness to attend all scheduled postoperative follow-up visits Exclusion Criteria: * Previous ocular surgery in the study eye * Corneal diseases or abnormalities that may affect corneal biomechanical measurements or keratometry * Glaucoma and ocular hypertension * Ocular trauma or active ocular inflammation

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Conditions

The condition(s) this trial relates to.

astigmatism cataract exfoliation syndrome exfoliation syndrome, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Astigmatism Cataract Pseudoexfoliation syndrome

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Eye Clinic Medic Jukic

    RECRUITING

    Split, Splitsko-dalmatinska County, 21000, Croatia

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