Apraxia
MONDO:0000665Apraxia is a neurological disorder characterized by the inability to perform tasks or movements, despite having the desire and physical ability to perform them. It is caused by damage to the brain, especially the parietal lobe, and can arise from many diseases, tumors, a stroke, or traumatic brain injury. In some cases it is present from birth. There are several types of apraxia, which may occur alone or together. These include: Buccofacial or orofacial apraxia is the inability to carry out facial movements on demand. This may include licking the lips, sticking out the tongue, whistling, coughing, or winking. Ideational apraxia is the inability to carryout learned, complex tasks with multiple, sequential movements. This may include dressing, eating, and bathing. Ideomotor apraxia is the inability to perform a learned task (such as using a tool) or communicate using gestures (like waving good-bye). Limb-kinetic apraxia is the inability to make fine, precise movements with an arm or leg. This may include buttoning a shirt or tying a shoe. Verbal apraxia is difficulty coordinating mouth and speech movements. Verbal apraxia may be acquired or present from birth. Constructional apraxia is the inability to copy, draw, or construct simple figures. Oculomotor apraxia is difficulty moving the eyes on command. Treatment of apraxia may include physical, speech, or occupational therapy. If apraxia occurs as a symptom of another disorder, treatment should be directed to the underlying condition.
Also known as: Apraxias, dyspraxia
34 clinical trials for this condition and its sub-types.
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Broader categories
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Walking retraining after ACL injury may stave off knee arthritis
Disease control Recruiting nowThis study tests whether a 6-week gait retraining program using real-time feedback can improve walking patterns and reduce early signs of knee osteoarthritis in people who have had ACL reconstruction. Seventy participants will be randomly assigned to receive either real-time biof…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Cord blood hope: new infusion option for kids with brain damage
Disease control AVAILABLEThis program gives children with brain disorders like cerebral palsy or stroke access to umbilical cord blood infusions. The treatment uses donated cord blood cells to help repair brain damage. Kids up to age 26 with normal immune function may qualify. The goal is to improve symp…
Sponsor: Joanne Kurtzberg, MD • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Spinal implant helps paralyzed patients walk again?
Disease control Recruiting nowThis study tests whether a fully implanted nerve stimulator can help people with incomplete spinal cord injury walk farther and more independently. Five participants will first be screened, then receive the implant and use it for up to two years. The device is turned on and off t…
Phase: NA • Sponsor: Louis Stokes VA Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Bilingual brain boost: new therapy targets language loss in dementia
Symptom relief Recruiting nowThis study tests a speech therapy program for bilingual Spanish-English or Spanish-Catalan speakers with primary progressive aphasia, a condition that slowly damages language abilities. Sixty participants will receive personalized script training via video sessions, while 30 othe…
Phase: NA • Sponsor: Stephanie Grasso • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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Could a tiny zap to the head help stroke survivors speak again?
Symptom relief Recruiting nowThis study tests whether a safe, mild electrical current applied to the scalp (tDCS) can make speech therapy work better for people who have trouble speaking after a stroke. 24 participants with apraxia of speech will receive both real and sham stimulation at different times to s…
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New speech therapy aims to help nonverbal kids with autism find their voice
Symptom relief Recruiting nowThis study tests a special speech therapy for minimally verbal children who have both autism and childhood apraxia of speech (a motor planning disorder). The therapy uses motor learning principles in a natural play-like setting. Researchers will enroll 20 children to see if this …
Phase: NA • Sponsor: MGH Institute of Health Professions • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Treadmill therapy may help stroke patients regain symmetry and speed
Symptom relief Recruiting nowThis study looks at whether walking on a treadmill can improve how stroke survivors move. Many people who have had a stroke walk unevenly and have different skin temperatures on their affected side. The researchers will measure changes in walking speed, endurance, and body heat p…
Phase: NA • Sponsor: University of Salamanca • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Can a simple walk test spot hidden risks in seniors?
Knowledge-focused Recruiting nowThis study looks at whether the Figure-of-8 Walk Test is a valid and reliable way to measure walking and balance in older adults with motoric cognitive risk syndrome (MCRS). MCRS combines slow walking speed with memory complaints and may signal future dementia. Researchers will t…
Sponsor: Balikesir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Your feet may reveal how well you walk and think as you age
Knowledge-focused Recruiting nowThis study looks at how the shape of your foot arch relates to the way you walk and your thinking skills in older adults. Researchers will measure foot structure, walking speed and steps, and reaction time in 50 people aged 65 and older. The goal is to better understand these con…
Sponsor: Balikesir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Walking and thinking: new study targets early dementia clues
Knowledge-focused Recruiting nowThis study looks at how adding a mental task (like counting backwards) affects walking and balance in older adults with motoric cognitive risk syndrome (MCRS). About 35 participants aged 65+ will do walking tests alone and while thinking. The goal is to better understand early si…
Sponsor: Balikesir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Brain scans and speech tests could unlock mystery of rare speech disorder
Knowledge-focused Recruiting nowThis study at Mayo Clinic looks at two different types of Progressive Apraxia of Speech, a condition that makes it hard to speak clearly. Researchers will use brain scans, speech assessments, and thinking tests in 47 adults to better tell these types apart. The goal is to improve…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Kids with DCD walk differently when multitasking – new study investigates
Knowledge-focused Recruiting nowThis study looks at how children aged 7 to 17 with developmental coordination disorder (DCD) walk while also doing a thinking task or a moving task. Researchers will compare their walking patterns to those of typically developing children. The goal is to gather detailed movement …
Phase: NA • Sponsor: University Ghent • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New brain scan study aims to unravel mysteries of speech disorder
Knowledge-focused Recruiting nowThis study uses advanced brain scans, including a special PET tracer called AV-1451, to track changes in the brains of 50 people with progressive apraxia of speech (a disorder that affects the ability to coordinate speech movements). Researchers at Mayo Clinic will compare these …
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC