Aneurysm or dilatation of ascending aorta

This study tested whether using a measure of oxygen in the blood (SvO2) to guide red blood cell transfusions during heart surgery could reduce how many patients receive transfusions. Over 600 adults undergoing on-pump cardiac surgery were randomly assigned to either standard rest…

This study tested whether making a small cut in the sac around the heart (posterior pericardiotomy) during open-heart surgery can prevent a common complication called atrial fibrillation. 210 adults having elective heart surgery in Yemen were randomly assigned to receive either t…

This study looked at 200 men and women who had surgery to repair a small ascending aortic aneurysm (5.0-5.5 cm). Researchers wanted to see if gender affects early and long-term outcomes like death, heart attack, or bleeding. The goal is to understand why women might have worse re…

This study looked at how well surgery works for people with an enlarged aorta (aneurysm) in the chest. Researchers compared outcomes in 50 patients who had surgery versus those who did not, tracking deaths and how fast the aorta grew over time. The goal was to better understand w…

This study tested a dye called pimonidazole to see if it can safely detect low oxygen levels (hypoxia) in the aorta of people having surgery for an ascending aortic aneurysm. Nine adults received the dye before surgery, and researchers measured how much of it was in the removed a…

This completed study looked at 101 patients with severe aortic stenosis who had a minimally invasive heart valve replacement (TAVR). Researchers wanted to see if the procedure was safe for patients who also had an enlarged ascending aorta (≥40 mm). They compared outcomes like dea…