Amyotrophic lateral sclerosis type 10
MONDO:0012790Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the TARDBP gene.
Also known as: ALS10, TARDBP amyotrophic lateral sclerosis, amyotrophic lateral sclerosis 10, with or without FTD, amyotrophic lateral sclerosis caused by mutation in TARDBP, amyotrophic lateral sclerosis type 10, frontotemporal lobar degeneration, TARDBP-related, Ftld-TDP, Tardbp-related, amyotrophic lateral sclerosis 10 with or without frontotemporal dementia
23 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
One-of-a-Kind ALS drug shows promise in first human test
Disease control CompletedThis trial tested a custom-made drug called nL-TARD-001 in one person with ALS caused by a specific genetic mutation in TARDBP. The drug is an antisense oligonucleotide designed to target the faulty gene. The study measured changes in muscle function, breathing, and thinking over…
Phase: PHASE1, PHASE2 • Sponsor: n-Lorem Foundation • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
-
Brain study sheds light on Parkinson's and tics
Knowledge-focused CompletedThis completed study from the National Institute of Neurological Disorders and Stroke aimed to better understand how the brain controls movement and what goes wrong in movement disorders like Parkinson's disease, Tourette's syndrome, and dystonia. Over 1,200 adults—both patients …
Phase: NA • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
-
Wrist-Worn gadget could help doctors monitor Parkinson's at home
Knowledge-focused CompletedThis study tested a wrist-worn device called the Personal KinetiGraph (PKG) to see if it can accurately measure movement problems in people with Parkinson's disease. Nineteen participants wore the device while researchers compared its readings to standard clinical tests and video…
Sponsor: Global Kinetics Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC