Amyotrophic lateral sclerosis type 10
MONDO:0012790Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the TARDBP gene.
Also known as: ALS10, TARDBP amyotrophic lateral sclerosis, amyotrophic lateral sclerosis 10, with or without FTD, amyotrophic lateral sclerosis caused by mutation in TARDBP, amyotrophic lateral sclerosis type 10, frontotemporal lobar degeneration, TARDBP-related, Ftld-TDP, Tardbp-related, amyotrophic lateral sclerosis 10 with or without frontotemporal dementia
23 clinical trials for this condition and its sub-types.
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Custom gene silencer takes aim at a rare form of ALS
Disease control ENROLLING_BY_INVITATIONThis study tests a personalized antisense oligonucleotide drug designed for a single person with ALS caused by a specific TARDBP gene mutation. The drug aims to reduce harmful TDP-43 protein and slow disease progression. The participant's clinical function, survival, and biomarke…
Phase: PHASE1, PHASE2 • Sponsor: n-Lorem Foundation • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Smart sleeve study aims to improve movement for nerve disease patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 1000 people with upper motor neuron disease who are about to receive the Cionic Neural Sleeve. The sleeve uses electrical stimulation to help muscles contract at the right time during movement. Researchers will track changes in health-related quality of life us…
Phase: NA • Sponsor: Cionic, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC