Amelogenesis imperfecta
MONDO:0019507Amelogenesis imperfecta (AI) represents a group of developmental conditions affecting the structure and clinical appearance of the enamel of all or nearly all the teeth in a more or less equal manner, and which may be associated with morphologic or biochemical changes elsewhere in the body.
8 clinical trials for this condition and its sub-types.
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Broader categories
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3D-Printed teeth: a better fit for kids?
Disease control CompletedThis trial tests whether 3D-printed crowns work better than standard stainless-steel crowns for restoring damaged first permanent molars in children. The study will compare how well each crown holds up, its effect on gum health, and how satisfied children and parents are with the…
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Vitamin d mouthwash shows promise for Kids' chalky teeth
Disease control CompletedThis study tested whether a vitamin D mouthwash can help repair weak spots on children's permanent teeth (a condition called molar incisor hypomineralization) and improve gum health. Thirty-two children over age 6 used either a vitamin D or placebo mouthwash. Researchers measured…
Phase: PHASE1 • Sponsor: Cairo University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Hunting for hidden genes behind tooth defects
Knowledge-focused CompletedThis study aims to discover new genes and mutations that cause isolated forms of amelogenesis imperfecta and dentinogenesis imperfecta—inherited conditions that affect tooth enamel and dentin. Researchers are using whole exome sequencing on participants who have these tooth disor…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Quick lesson boosts Dentists-in-Training on tricky tooth condition
Knowledge-focused CompletedThis study tested whether a 30-minute interactive lesson could improve dental interns' understanding of Molar-Incisor Hypomineralization (MIH), a condition that causes weak spots on teeth. Two hundred dental interns from Future University in Egypt took a quiz before and after the…
Phase: NA • Sponsor: Future University in Egypt • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC