Amblyopia

This study tests whether a home-based computer program, called Gabor-based perceptual learning, can improve vision in adults with amblyopia (lazy eye). Participants aged 18-39 will be randomly assigned to either start training immediately or after a 12-week delay, with all receiv…

This trial tests whether adding a mild electrical brain stimulation to augmented reality-based vision therapy can improve vision in adults aged 18 to 35 with lazy eye (anisometropic amblyopia). Participants will use special augmented reality glasses that encourage both eyes to wo…

This early-stage trial tests whether adding the drug valproate to standard patching therapy can improve vision in children aged 8 to 17 with lazy eye (amblyopia). Participants will take valproate or a placebo daily for 8 weeks while patching the stronger eye. The study aims to se…

This study tests whether adding specially designed digital games to standard eye-patch therapy can improve vision and motivation in children aged 4 to 7 with lazy eye (amblyopia). Sixty-six children will either wear an eye patch alone or combine it with a touchscreen or augmented…

This study tests whether using red/green glasses with video games can improve vision in people with amblyopia (lazy eye). Sixty participants will use either these glasses, an eye patch with a tablet, or standard patching for 2 hours daily over 4 months. The goal is to see if bino…

This study tests whether watching special 3D movies at home can improve vision in children aged 3 to 7 with lazy eye (amblyopia). Half the children will watch the movies on a handheld 3D screen, while the other half will use a standard eye patch. The goal is to see if the movie m…

This study tests whether wearing the right glasses can improve vision in adults with amblyopia (lazy eye). Researchers will measure how well participants see before, during, and after wearing custom spectacles. The goal is to see if the adult brain can still learn to see better w…

This study tests whether playing special binocular games on a tablet for one hour a day, five days a week, can improve vision in children aged 4 to 10 with amblyopia (lazy eye). The games show high-contrast images to the weaker eye and low-contrast images to the stronger eye, tra…

This study tests whether playing special video games or watching movies through a virtual reality headset can improve vision in children aged 8 to 12 with amblyopia (lazy eye). About 252 kids will be randomly assigned to use one of two VR treatments or just wear glasses. The main…

This study looks at the best way to treat lazy eye (amblyopia) in children aged 3 to under 13. Some children get glasses and an eye patch at the same time, while others start with glasses alone and add patching later if needed. The goal is to see if both approaches lead to simila…

This study tests whether watching specially designed movies through a virtual reality headset for 1 hour a day, 6 days a week, can improve vision in children with lazy eye (amblyopia) as effectively as the standard treatment of wearing an eye patch for 2 hours daily. The trial in…

This study tests a new digital therapy called AmblyoFix for treating lazy eye (amblyopia) in children aged 7 to 12. The therapy uses special software and red-blue glasses to play visual games that stimulate the weaker eye. Researchers will compare results to a group of children w…

This study tests a new patch-free treatment for lazy eye (amblyopia) in children aged 3 to 12. Instead of wearing a sticky patch over the good eye, kids wear special glasses that blur the good eye while they watch videos. The goal is to see if this method improves vision better t…

This study tests a home-based video treatment called Curesight for children aged 8 to 12 with amblyopia (lazy eye). The treatment works by showing videos where the stronger eye sees a blurred central area while the weaker eye sees the full clear image, encouraging the brain to us…

This program provides comprehensive low vision rehabilitation services to children aged 3 to 21 with vision impairment. Participants are prescribed optical devices and trained to use them, with the goal of improving their visual functioning and ability to read. The program aims t…

This study tests whether a non-invasive brain stimulation technique called tDCS can safely improve vision in 100 children aged 4-14 with lazy eye (amblyopia) that hasn't improved with standard patching. Children will receive either real or sham tDCS over three sessions, and their…

This pilot study tests whether a non-invasive headset that delivers mild electrical stimulation to nerves behind the ear can safely improve sleep in adults who are blind or severely sight impaired. Sixty participants will use the device for 30 minutes a day, five times a week for…

This study looks at whether adding fluoxetine (a common antidepressant) to standard eye patching can improve and maintain vision in people over 10 with lazy eye (amblyopia). Researchers will use special eye scans and brain tests to measure changes. The goal is to find a new way t…

This study is testing whether playing video games and doing special vision exercises can improve eyesight in both children and adults with amblyopia (lazy eye). Researchers will measure changes in visual acuity, depth perception, and contrast sensitivity before and after the trai…

This study tests a smartphone-based tool called VisionWay that helps people with visual impairments choose the most accessible walking path before they start walking. Researchers will ask participants to walk different routes on a university campus and rate sidewalk features like…

This study looks at how well people with amblyopia (lazy eye) or strabismus (crossed eyes) see before, during, and after common treatments like patching, glasses, or surgery. Researchers will measure things like sharpness, contrast, and reading ability. The goal is to better unde…

This study looks at eye problems in people with craniosynostosis, a condition where skull bones close too early. Researchers will check for issues like crossed eyes, lazy eye, and pressure inside the head. The goal is to better understand these eye problems to help improve care.

This study looks at how older adults with and without vision problems step over obstacles of different heights and colors. Researchers want to understand how vision and eye movements affect walking to help prevent falls. About 200 adults who can walk on their own will take part.

This study will collect data from 500 people with amblyopia (lazy eye) who are using Luminopia, an FDA-approved software treatment that works by showing different images to each eye. Researchers want to see how vision changes over time, how well patients stick with the treatment,…