VR video games could be the new treatment for lazy eye in children

NCT ID NCT06524882

Recruiting now Disease control Sponsor: Jaeb Center for Health Research Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether playing special video games or watching movies through a virtual reality headset can improve vision in children aged 8 to 12 with amblyopia (lazy eye). About 252 kids will be randomly assigned to use one of two VR treatments or just wear glasses. The main goal is to see if the VR treatments improve vision more than glasses alone after 18 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vivid Vision (VR dichoptic video games) and Luminopia (VR dichoptic movies/shows)
What this could lead to: If successful, this could offer a non-invasive, engaging treatment option for older children with amblyopia, potentially improving vision without eye patches or drops.
What could go wrong: This is a Phase 3 trial, but the treatment is still experimental. It may not work for all children, and the improvement in vision might be modest. The novelty of VR could also affect adherence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amblyopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMBLYOPIA

Contacts and locations

Locations

Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITING

Chicago, Illinois, 60611, United States
Arkansas Childrens
RECRUITING

Little Rock, Arkansas, 72202, United States
Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States
Boston Children's Hospital Waltham
RECRUITING

Boston, Massachusetts, 02453, United States
Boston Medical Center
RECRUITING

Boston, Massachusetts, 02118, United States
Children's Mercy Hospitals and Clinics
RECRUITING

Kansas City, Missouri, 64108, United States
Cincinnati Children's Hospital
RECRUITING

Cincinnati, Ohio, 45229, United States
Cole Eye Institute
RECRUITING

Cleveland, Ohio, 44195, United States
Conestoga Eye
RECRUITING

Lancaster, Pennsylvania, 17601, United States
Duke University Eye Center
RECRUITING

Durham, North Carolina, 27710, United States
Greater Baltimore Medical Center
RECRUITING

Baltimore, Maryland, 21204-5809, United States
Illinois College of Optometry
RECRUITING

Chicago, Illinois, 60616, United States
Indiana School of Optometry
RECRUITING

Bloomington, Indiana, 47405, United States
Mayo Clinic Department of Ophthalmology
RECRUITING

Rochester, Minnesota, 55905, United States
McFarland Eye Care Center
RECRUITING

Little Rock, Arkansas, 72205, United States
Michigan College of Optometry at Ferris State Univ
RECRUITING

Big Rapids, Michigan, 49307, United States
Midwestern University Eye Institute
RECRUITING

Glendale, Arizona, 85308, United States
Midwestern University Eye Institute
RECRUITING

Downers Grove, Illinois, 60515, United States
NYU Langone Health
RECRUITING

New York, New York, 10017, United States
New England College of Optometry
RECRUITING

Boston, Massachusetts, 02115, United States
Nova Southeastern University College of Optometry, The Eye Institute
RECRUITING

Fort Lauderdale, Florida, 33382, United States
OHSU Casey Eye Institute
RECRUITING

Portland, Oregon, 97239, United States
Ohio State University College of Optometry
RECRUITING

Columbus, Ohio, 43210-1280, United States
Pediatric Ophthalmology of Erie
RECRUITING

Erie, Pennsylvania, 16501, United States
Pediatric Ophthalmology, P.C.
RECRUITING

Grand Rapids, Michigan, 49546, United States
Phoenix Children's Medical Group - Ophthalmology
RECRUITING

Scottsdale, Arizona, 85255, United States
PineCone Vision Center
RECRUITING

Sartell, Minnesota, 56377, United States
Progressive Eye Care
RECRUITING

Lisle, Illinois, 60532, United States
Rainbow Babies and Children's Hospital Dept of Ophth
RECRUITING

Mayfield Heights, Ohio, 44124, United States
River View Family Eyecare
RECRUITING

Albany, Oregon, 97321, United States
Salus University/Pennsylvania College of Optometry
RECRUITING

Philadelphia, Pennsylvania, 19141, United States
San Antonio Eye Center
RECRUITING

San Antonio, Texas, 78215, United States
Southern College of Optometry
RECRUITING

Memphis, Tennessee, 38104, United States
Spokane Eye Clinical Research
RECRUITING

Spokane, Washington, 99204, United States
Stanford University
RECRUITING

Palo Alto, California, 94303, United States
State University of New York, College of Optometry
RECRUITING

New York, New York, 10036, United States
Storm Eye Institute
RECRUITING

Mt. Pleasant, South Carolina, 29464, United States
UAB Pediatric Eye Care; Birmingham Health Care
RECRUITING

Birmingham, Alabama, 35294, United States
Univ of California, Irvine- Gavin Herbert Eye Institute
RECRUITING

Irvine, California, 92697, United States
Univ. of California- Berkeley
RECRUITING

Berkeley, California, 94720, United States
University Eye Center at Ketchum Health
RECRUITING

Anaheim, California, 92807, United States
University of Arizona
RECRUITING

Tucson, Arizona, 85711, United States
University of California San Francisco Department of Ophthalmology
RECRUITING

San Francisco, California, 94143, United States
University of California, Davis
RECRUITING

Sacramento, California, 95817, United States
University of Houston - College of Optometry
RECRUITING

Houston, Texas, 77204, United States
University of Houston College of Optometry
RECRUITING

Houston, Texas, 77204, United States
University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States
University of Kansas Dept of Ophthalmology
RECRUITING

Prairie Village, Kansas, 66208, United States
University of Minnesota-Minnesota Lions Children's Eye Clinic
RECRUITING

Minneapolis, Minnesota, 55454, United States
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68114, United States
University of North Carolina
RECRUITING

Chapel Hill, North Carolina, 27599, United States
University of North Dakota
RECRUITING

Grand Forks, North Dakota, 58202, United States
University of South Florida (USF) Eye
RECRUITING

Tampa, Florida, 33620, United States
Virginia Pediatric Eye Center
RECRUITING

Norfolk, Virginia, 23502, United States
Western University College of Optometry
RECRUITING

Pomona, California, 91766, United States
Wills Eye Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
Wilmer Eye Institute
RECRUITING

Baltimore, Maryland, 21287-9028, United States
Zenith Vision Development Center
RECRUITING

Duluth, Minnesota, 55811, United States

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