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Adenomyosis
MONDO:0010888The growth of endometrial tissue inside the muscular wall of the uterine corpus. Clinical manifestations include pain, dysmenorrhea, and menorrhagia.
Also known as: adenomyosis of the uterus, adenomyosis of uterus, endometriosis (disease) of myometrium, endometriosis interna, endometriosis of myometrium, endometriosis of uterus, endometriosis, myometrium, myometrium endometriosis (disease)
47 clinical trials for this condition and its sub-types.
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Broader categories
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New IUD combo aims to stop displacement in adenomyosis
Disease control CompletedThis trial tests whether combining a hormone-releasing IUD with an anchoring IUD can prevent the device from slipping out of place in women with adenomyosis, a condition that causes pelvic pain and heavy bleeding. The study includes 270 women with different uterine cavity depths,…
Phase: NA • Sponsor: Wenzhou People's Hospital • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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New handmade IUD aims to stay put in women with adenomyosis
Disease control CompletedThis study tested a handmade frameless IUD that releases the hormone levonorgestrel in 15 women at high risk of IUD expulsion due to conditions like adenomyosis or heavy bleeding. The device was made by combining an anchor system with a standard IUD after removing its T-shaped ar…
Sponsor: Yu Wang • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Surgeons test safer way to remove oversized uteri without large cuts
Disease control CompletedThis study tested a new surgical method to remove very large uteri (over 20 weeks size) during total laparoscopic hysterectomy. The technique uses a cold knife to cut the uterus into a long strip that can be pulled out through the vagina, avoiding large abdominal incisions. Twent…
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Smart pain monitor may reduce opioid use in endometriosis surgery
Symptom relief CompletedThis completed study tested whether a special pain monitor (NOL index) could help doctors give the right amount of pain medication during laparoscopic endometriosis surgery. The goal was to reduce total painkiller use and improve recovery. The study included 125 premenopausal wom…
Phase: NA • Sponsor: Prof Urs Zingg • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New vaginal surgery technique may reduce pain after hysterectomy
Symptom relief CompletedThis study compared two types of minimally invasive hysterectomy: vNOTES (done through the vagina) and conventional laparoscopic hysterectomy (done through small belly cuts). About 90 women having hysterectomy for non-cancer reasons took part. The goal was to see which method cau…
Phase: NA • Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Robot-Assisted hysterectomy shows promise in small trial
Symptom relief CompletedThis study tested the safety and effectiveness of the DEXTER robotic system in 52 patients having a hysterectomy (removal of the uterus) and related surgery for non-cancerous conditions. The main goals were to see if the robotic procedure could be completed without switching to o…
Sponsor: Distalmotion SA • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Keyhole surgery blood loss study compares tying techniques
Knowledge-focused CompletedThis study looked at 60 women aged 35 to 60 who had a hysterectomy (removal of the uterus) through small cuts in the belly (laparoscopy). The goal was to compare two different methods of tying off the uterine arteries to see which one led to less blood loss during surgery. The re…
Phase: NA • Sponsor: Mostafa Bahaa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Fertility after fibroid embolization: new data from 46 women
Knowledge-focused CompletedThis study looked back at 46 women who had a procedure called uterine artery embolization to treat fibroids. The goal was to see how often women later had a baby and what pregnancy complications occurred. The researchers reviewed medical records from one hospital in France to gat…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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New study tests heat treatment for painful uterine condition
Knowledge-focused CompletedThis study looked at how radiofrequency ablation (using heat) affects adenomyosis tissue in 15 women who were already scheduled for a hysterectomy. The goal was to see how well the treatment destroys the abnormal tissue by examining it under a microscope after surgery. The study …
Phase: NA • Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New stitch tool tested in robot surgeries shows promise
Knowledge-focused CompletedThis study tested a special stitch device (STRATAFIX Spiral PDS Plus) used in robot-assisted surgeries for weight loss (sleeve gastrectomy) and hysterectomy. 161 adults took part. The main goal was to see how well it controlled bleeding after stitching. Doctors also rated how eas…
Sponsor: Ethicon, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Robots vs. surgeons: which is better for hysterectomy?
Knowledge-focused CompletedThis study compared robot-assisted laparoscopy using the Senhance Surgical System to conventional laparoscopy for hysterectomy and other uterine surgeries. Researchers measured operating time, blood loss, and safety in 78 patients. The goal was to see if the robot offers advantag…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New surgical order may keep vagina longer after hysterectomy
Knowledge-focused CompletedThis study tested whether starting a hysterectomy by cutting the back of the vagina (posterior colpotomy first) helps keep the vagina longer compared to the usual method. Eighty women having a hysterectomy for non-cancer reasons took part. The main goal was to measure any differe…
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Surgeons try High-Tech goggles to spot hidden tumors during keyhole surgery
Knowledge-focused CompletedThis completed study tested whether augmented reality (AR) can help surgeons during laparoscopic surgery for uterine fibroids or adenomyosis. AR overlays images from pre-surgery scans onto the live video feed, potentially making it easier to see and remove benign tumors. Forty pa…
Phase: NA • Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:26 UTC