Adenomyosis
MONDO:0010888The growth of endometrial tissue inside the muscular wall of the uterine corpus. Clinical manifestations include pain, dysmenorrhea, and menorrhagia.
Also known as: adenomyosis of the uterus, adenomyosis of uterus, endometriosis (disease) of myometrium, endometriosis interna, endometriosis of myometrium, endometriosis of uterus, endometriosis, myometrium, myometrium endometriosis (disease)
48 clinical trials for this condition and its sub-types.
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Broader categories
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Can a water barrier make microwave ablation safer for the womb?
Disease control OngoingThis trial compares two microwave ablation techniques for treating uterine adenomyosis, a condition where uterine tissue grows into the muscle wall, causing pain and heavy bleeding. One group receives the standard approach with saline injected around the uterus, while the other a…
Phase: NA • Sponsor: Peking University Aerospace Center Hospital • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New robot could transform hysterectomy surgery
Disease control OngoingThis study is testing a new robotic system, the Medtronic Hugo™, for performing hysterectomies. It includes 70 patients with conditions like uterine fibroids, endometriosis, or certain cancers. The goal is to see if the robot is safe and can complete the surgery without switching…
Phase: NA • Sponsor: Medtronic - MITG • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Bagged and fragmented: a Scar-Free way to remove large uteri?
Disease control OngoingThis study tests a new surgical technique to remove large uteri through the vagina using a sealed bag and electric fragmentation. The goal is to avoid abdominal scars and prevent the spread of tissue fragments. Twenty-five women aged 38 to 52 with large uteri are participating. T…
Sponsor: Chang Zhou • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Can watching videos before surgery calm nerves?
Symptom relief ENROLLING_BY_INVITATIONThis trial is testing whether watching educational videos before minimally invasive gynecologic surgery can lower patient anxiety. Participants are randomly assigned to either watch the videos or receive standard counseling alone. The study measures anxiety and preparedness throu…
Phase: NA • Sponsor: UConn Health • Aim: Symptom relief
Last updated Aug 05, 2026 00:00 UTC
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Ice pack on the belly may ease pain after keyhole hysterectomy
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether applying an ice pack to the lower abdomen after vNOTES hysterectomy can lower pain and reduce the need for painkillers. 122 women having surgery for benign conditions will be randomly assigned to receive either standard care or standard care plus ice pack…
Phase: NA • Sponsor: Erzincan Military Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Vitamin c IV may curb blood loss in hysterectomy
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether giving vitamin C through an IV before and during a hysterectomy can reduce blood loss. Forty women with fibroids or adenomyosis will receive either vitamin C or a placebo. Researchers will measure blood loss during surgery and check if vitamin C helps mai…
Phase: NA • Sponsor: Queen Savang Vadhana Memorial Hospital, Thailand • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Could a steroid nerve block ease pain after fibroid procedure?
Symptom relief OngoingThis study looks at whether adding a steroid to a nerve block can better control pain after a procedure that treats uterine fibroids or adenomyosis. About 28 women aged 30 to 60 will receive either a standard numbing nerve block or one with added steroids. Researchers will measur…
Phase: EARLY_PHASE1 • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Can brain scans unlock the mystery of chronic pelvic pain?
Knowledge-focused TerminatedThis study uses functional magnetic resonance imaging (fMRI) to examine brain activity in women with chronic pelvic pain and endometriosis. Researchers will also conduct psychological tests to assess anxiety, depression, and pain catastrophizing. The goal is to understand how chr…
Phase: NA • Sponsor: KK Women's and Children's Hospital • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC
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Scientists seek better way to classify uterine condition
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to improve how doctors classify adenomyosis, a condition that causes heavy bleeding and pain. Researchers will compare ultrasound, MRI, and tissue results from 32 women aged 35-55 who are scheduled for hysterectomy. The goal is to link imaging findings with sympto…
Sponsor: Kafrelsheikh University • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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Resident's journey to master scarless hysterectomy under the microscope
Knowledge-focused OngoingThis study watches a single gynecology resident as they learn to perform a hysterectomy through the vagina using a special camera, leaving no belly scars. The goal is to see how quickly the resident improves, measuring surgery time and any complications. Nineteen women with benig…
Sponsor: Cukurova University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New study investigates why some women with adenomyosis suffer more pain
Knowledge-focused OngoingThis study looks at how the nervous system may become overly sensitive (central sensitization) in women with adenomyosis, a condition where uterine tissue grows into the muscle wall. Researchers will follow 1,200 women aged 18-50 for 12 months to see how common this sensitivity i…
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC