New study investigates why some women with adenomyosis suffer more pain

NCT ID NCT07455721

Ongoing Knowledge-focused Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the nervous system may become overly sensitive (central sensitization) in women with adenomyosis, a condition where uterine tissue grows into the muscle wall. Researchers will follow 1,200 women aged 18-50 for 12 months to see how common this sensitivity is and whether it affects pain and treatment success. The goal is to better understand pain patterns and improve care.

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Conditions

The condition(s) this trial relates to.

adenomyosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOMYOSIS

Contacts and locations

Locations

AOR San Carlo

Potenza, Potenza, 85100, Italy
ARNAS Ospedale Civico di Palermo

Palermo, Palermo, 90127, Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Bologna, 40138, Italy
IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Milano, 20122, Italy
IRCCS Ospedale San Raffaele di Milano

Milan, Milano, 20132, Italy
Presidio Ospedaliero Universitario "Santa Maria della Misericordia", Azienda Sanitaria Universitaria Friuli Centrale, Udine

Udine, Udine, 33100, Italy
Università degli Studi "Magna Grecia" di Catanzaro, Azienda Ospedaliero-Universitaria Renato Dulbecco

Catanzaro, Catanzaro, 88100, Italy
Università di Cagliari, Dipartimento di Scienze Chirurgiche

Cagliari, Cagliari, 09124, Italy
Università di Firenze, Ospedale Santa Maria Annunziata

Florence, Firenze, 50012, Italy
Università di Milano, Ospedale Macedonio Melloni

Milan, Milano, 20129, Italy
Università di Roma La Sapienza, Policlinico Umberto I

Roma, Roma, 00161, Italy
Università di Roma Tor Vergata, Policlinico Tor Vergata

Roma, Roma, 00133, Italy
Università di Siena, Policlinico Santa Maria alle Scotte

Siena, Siena, 53100, Italy
Università di Verona, Ospedale Borgo Roma

Verona, Verona, 37126, Italy

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