Acute cholangitis

This study looked at 410 patients with a bile duct infection (cholangitis) who had a procedure to drain the bile duct. It compared giving antibiotics for just 1 day versus the usual 4 to 7 days. The goal was to see if the shorter course is just as good at curing the infection, wh…

This study tested whether analyzing a patient's DNA and RNA could help doctors pick the right drug for inflammatory diseases that don't fit standard categories. 32 adults with at least two affected organs (including skin) received one of six targeted therapies based on their mole…

This study looked at 484 high-risk surgical patients with acute cholecystitis (gallbladder inflammation) who first received a standard drainage tube through the skin. Some then had a newer procedure using an endoscope to place a metal stent inside the gallbladder. Researchers com…

This study tested a procedure called EUS-guided gallbladder drainage (EGBD) as an alternative to gallbladder removal surgery for 30 adults with acute cholecystitis (gallbladder inflammation). The goal was to see if it could safely resolve symptoms like fever and pain without need…

This study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …

This study looked at 304 patients with mild to moderate acute cholangitis, a serious bile duct infection. Researchers compared performing ERCP (a drainage procedure) within 24 hours versus waiting 24 to 48 hours. The goal was to see if faster treatment reduces deaths within 30 da…

This study looked at whether giving antibiotics after gallbladder removal surgery helps prevent infections in people with mild to moderate gallbladder inflammation. Over 400 adults took part, receiving either antibiotics or no medication after surgery. The goal was to see if anti…

This study tested two types of endoscopes used in ERCP, a procedure to treat bile duct and pancreas problems. One scope had a single-use plastic cover on its tip, while the other was a standard reusable scope. Researchers compared how well each worked and how often complications …

This study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…

This study tested whether a low-dose CT scan, enhanced with deep learning image reconstruction, can diagnose acute abdominal conditions as accurately as a standard CT scan. 246 adults with abdominal pain received both scans, and the low-dose version used less than 30% of the usua…

This completed study tested a device called NvisionVLE® that helps doctors see bile duct details during a procedure called ERCP. Only 3 adults who had the procedure between 2017 and 2019 took part. The goal was to check if the device is safe and can better find abnormalities to g…

This early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …

This study tested whether a green dye injected into the blood can help surgeons see bile ducts better during gallbladder removal for acute cholecystitis, compared to the standard contrast dye. 156 adults with mild to moderate gallbladder inflammation took part. The goal was to se…

This study tested whether adding acupuncture to standard anti-nausea drugs could better prevent nausea and vomiting after laparoscopic gallbladder removal. 270 adults scheduled for surgery received either acupuncture plus standard drugs or standard drugs alone. The goal was to se…

This study looked at whether emergency gallbladder removal (laparoscopic cholecystectomy) can be performed as an outpatient procedure, meaning patients go home the same day. Researchers measured patient satisfaction using a simple scale. The study enrolled 25 adults with acute ch…

This study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…

This study tested a personalized dose of a dye called indocyanine green (ICG) to help surgeons see bile ducts more clearly during emergency gallbladder removal. 21 patients with acute cholecystitis received a dye dose calculated from their MRI scans. The goal was to improve surgi…

This study tested a different surgical method (fundus-first) versus the standard method for removing difficult gallbladders in 174 adults. The goal was to see if the new method lowers the risk of bile duct injury, a serious complication. Participants had conditions like acute cho…

This study tested whether using a needle to drain a swollen gallbladder during laparoscopic removal makes the operation easier and safer. 70 patients with acute cholecystitis, gallbladder mucocele, or empyema were randomly assigned to have their gallbladder drained or not. The go…

This study tested whether adding acupuncture at a specific point (GB34) to standard medical care could help people with mild gallbladder inflammation (acute cholecystitis). Thirty hospitalized adults received either acupuncture plus usual treatment or usual treatment alone. The g…

This completed study looked at how the social networks of caregivers affect their stress and health when caring for someone with an inherited disease. Researchers surveyed over 680 participants, including family members and formal caregivers, to understand caregiving burden and s…

This study looked at a new device called AE05ML that helps surgeons place clips on blood vessels and other tissues during keyhole surgery. The goal was to see if the device is safe and works well. A total of 161 adults took part in the study.

This completed observational study at Uşak University examined 150 adults hospitalized in the endocrinology department. Researchers measured breathing, muscle strength, pain, fatigue, sleep quality, physical activity, balance, and nerve function. The goal was to better understand…

This study looked at 1435 patients with acute cholangitis (a bile duct infection) who had an ERCP procedure. Researchers analyzed bile samples to understand which bacteria were causing the infections and how resistant they were to antibiotics. The goal was to find patterns that c…

This study looked at how emergency general surgery affects pregnant women and their unborn babies. Researchers planned to follow pregnant women who needed surgery for problems like appendicitis or gallbladder disease. The goal was to learn more about the safety of these surgeries…

This study looked back at the medical records of 609 people treated for gallbladder inflammation (cholecystitis) in Villavicencio, Colombia, between 2019 and 2022. The goal was to understand how quickly patients received care, what treatments they got, and how many had complicati…

This study looked at 559 patients who had their gallbladder removed laparoscopically to find out when surgical drains are truly needed. Drains are sometimes placed to prevent fluid buildup or infection, but many studies show they aren't always necessary. The goal is to help docto…