Acute apical periodontitis
MONDO:0001338Also known as: acute apical periodontitis of pulpal origin
27 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Custom 3D-Printed bone grafts could improve dental implant success
Disease control Not yet recruitingThis study looks at how well 3D printed bone grafts work for supporting dental implants in people with gum disease or bone loss. Researchers will check if the implants stay stable and how much the graft shrinks over 1 to 6 years. About 100 healthy adults who already received this…
Sponsor: University of Guarulhos • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Gum disease in 95% of pregnant women: can simple brushing lessons help?
Disease control Not yet recruitingThis study tests a new program that teaches pregnant women in Bangladesh how to care for their teeth and gums during routine prenatal visits. Over 95% of pregnant women in Bangladesh have gum disease, but oral health is not part of standard pregnancy care. The study will compare …
Phase: NA • Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Blood clot upgrade: new gel may regrow tooth tissue
Disease control Not yet recruitingThis study tests whether a gel made from a patient's own blood (platelet-rich fibrin) can help regenerate the inner part of infected or dead teeth in adults. 57 participants will receive either the gel or a standard blood-clot treatment. The goal is to see if the gel reduces infe…
Phase: NA • Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Mail-In breath test could end bad breath diagnosis travel
Diagnosis Not yet recruitingThis study tests whether breath samples collected in special bags remain stable for up to 7 days, which could allow people with bad breath (halitosis) to provide samples from home instead of traveling to a clinic. Researchers will compare gas levels measured right away and after …
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC
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Gum disease detection: could a questionnaire replace the Dentist's probe?
Diagnosis Not yet recruitingThis study will check if a simple questionnaire can accurately identify gum disease in adults. About 291 participants in Saudi Arabia will fill out the questionnaire and then have a standard dental exam. The goal is to see how well the questionnaire matches the exam results, whic…
Sponsor: Universiti Sains Malaysia • Aim: Diagnosis
Last updated Jun 27, 2026 09:05 UTC
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AI-Powered selfies could spot gum disease without a dentist visit
Diagnosis Not yet recruitingThis study will enroll 2,000 adults to see if non-invasive methods like smartphone photos, dental X-rays, and questionnaires can accurately detect gum disease compared to a standard clinical exam. Researchers will use artificial intelligence to analyze the images and combine data…
Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University • Aim: Diagnosis
Last updated Jun 26, 2026 16:01 UTC
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New tooth filling may ease root canal pain
Symptom relief Not yet recruitingThis study tests whether a newer bioceramic filling material reduces pain after root canal treatment better than the standard calcium hydroxide filling. Twenty-eight adults with painful lower molar infections will receive one of the two fillings during their root canal. Pain leve…
Phase: NA • Sponsor: Future University in Egypt • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Which pill eases root canal pain best? new study tests two options
Symptom relief Not yet recruitingThis study compares two single-dose pain relievers—piroxicam and prednisolone—given before a root canal to see which one reduces pain better afterward. Sixty adults with an inflamed tooth nerve and infection will take one of the drugs right before treatment. The goal is to find a…
Phase: PHASE4 • Sponsor: RANA AHMAD • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Dental AI learns from 150 patients in new data study
Knowledge-focused Not yet recruitingThis study gathers mouth pictures from 150 adults with different gum conditions to teach an AI system how to spot gum disease. Participants simply have their teeth and gums photographed with a special probe. No treatment or medication is involved—just data collection to improve f…
Phase: NA • Sponsor: LuminX • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Gum disease smarts: do dental students know more than psychology students?
Knowledge-focused Not yet recruitingThis study looks at how much final-year dentistry and psychology students know about gum disease (periodontitis) and whether that knowledge is linked to their own gum health. About 60 students will fill out a questionnaire and get a dental check-up. The goal is to see if more kno…
Sponsor: Universitat Internacional de Catalunya • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC