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129572 trials found · Page 6383 of 6479
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Porridge study: which corn meal keeps you full longer?
Knowledge-focused CompletedThis study is designed to test the hypothesis that whole-grain forms of maize meal enhance and prolong satiety post-meal consumption.
Sponsor: PepsiCo Global R&D • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New drug ATX101 takes first step: safety check in healthy people
Knowledge-focused CompletedThe main objective of this study is to assess the safety and tolerability of intravenously administered ATX101 in healthy adults following single ascending doses of ATX101. The pharmacokinetic profile of ATX101 and its metabolites will also be investigated.
Phase 1 • Sponsor: Aurobac Therapeutics SAS • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Healthy volunteers help uncover drug interactions for new compound
Knowledge-focused CompletedThis study is conducted to assess the effect of itraconazole, rifampin, and acid-reducing agents on INCB161734 pharmacokinetics when administered orally in healthy participants.
Phase 1 • Sponsor: Incyte Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Ketone showdown: which supplement wins in the body?
Knowledge-focused OngoingThe purpose of this study is to examine how the body absorbs, digests, and metabolizes three different investigational ketone dietary supplements (ketone monoester, ketone tri-ester, ketone salt) and to assess gastrointestinal tolerance or other adverse effects. This study is con…
Sponsor: NeuroEnergy Ventures, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New drug SEP-631 tested for safety in healthy people
Knowledge-focused CompletedThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and food effects of oral SEP-631 in healthy adult volunteers.
Phase 1 • Sponsor: Septerna, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Pfizer begins first human tests of mystery pill PF-07940369
Knowledge-focused CompletedThe purpose of this study is to learn about the safety and tolerability of a study medicine called PF-07940369 when it is taken by mouth in different amounts and/or at multiples times a day by healthy adult participants. The study will also look at the pharmacokinetics of PF-0794…
Phase 1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Blood pressure cuff could spot heart trouble in lung clot patients
Knowledge-focused CancelledPulmonary embolism impacts over 1 in 1000 adults annually and is the third leading cause of cardiovascular death after heart attack and stroke. The consequence of each PE is widely variable. Physiologically, the morbidity and mortality of PE is ultimately caused by failure of the…
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Can a tape measure replace a joint angle tool for wall squats?
Knowledge-focused CompletedThe wall squat exercise has been used in several research studies to help lower blood pressure. However, setting up the correct squat position often involves using a joint angle-measuring tool called a goniometer to get the knee at exactly the right angle. To set up the wall squa…
Sponsor: Northumbria University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Scientists compare belly, arm, and thigh shots for new drug
Knowledge-focused CompletedThe main objective of the study is to assess the relative bioavailability of KAI-9531 subcutaneous (SC) injection in the upper arm and thigh compared to the abdomen.
Phase 1 • Sponsor: Kailera • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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New drug MRX1 tested in healthy volunteers for safety and absorption
Knowledge-focused CompletedThe purpose of this study is to assess the pharmacokinetics, safety, tolerability and food effect of investigational drug MRX1 in healthy adults.
Phase 1 • Sponsor: Tiamat Australia Pty Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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New combo flu pill put to the test in healthy volunteers
Knowledge-focused Recruiting nowThis study aims to evaluate the safety and pharmacokinetic profile of the active ingredients Ingavirin forte, capsules, 90 mg + 20 mg (Valenta Pharm JSC, Russia) relative to single-entity Drug Ingavirin, capsules, 90 mg following administration under fasting and fed conditions.
Phase 1 • Sponsor: Valenta Pharm JSC • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Mouthwash without alcohol: gentle on gums?
Symptom relief CompletedThe objective of this study is to evaluate the oral soft and hard tissue tolerance after 14 days of a twice daily regimen of brushing and rinsing with essential oil containing alcohol free mouthwashes versus a control.
Sponsor: Kenvue Brands LLC • Aim: Symptom relief
Last updated Jun 26, 2026 14:50 UTC
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Healthy volunteers test new cancer Drug's body processing
Knowledge-focused CompletedThe main purpose of this study is to measure how much olomorasib gets into the bloodstream and how long it takes the body to get rid of it. Healthy participants will take olomorasib by mouth. The study will last about 7 weeks and will include 10 back-to-back overnight stays in th…
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Healthy volunteers help test if food changes drug absorption
Knowledge-focused CompletedThe goal of this clinical trial is to Assess the Effect of Food on the Pharmacokinetics (PK) of D3S-001 in Healthy Adult Participants. The main question\[s\] it aims to answer are: 1. Evaluate the PK of D3S-001 administered in the fasted and fed state in healthy adult participa…
Phase 1 • Sponsor: D3 Bio (Wuxi) Co., Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Heart data harvest: no treatment, just software testing
Knowledge-focused CompletedThis is a prospective, observational study collecting data from routine clinical care. The information gathered will be used to support the evaluation of a software-based tool. No investigational procedures or treatments are introduced, and all data are obtained as part of standa…
Sponsor: Anumana, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Healthy volunteers test new diabetes drug formulation
Knowledge-focused CompletedPhase 1 study evaluating the safety, tolerability, and pharmacokinetics of lobeglitazone administered as M107 Orally Disintegrating Tablet and Duvie tablet in healthy adult participants under fasted and fed conditions.
Phase 1 • Sponsor: Aclipse Two Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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App for cancer depression fails to launch: trial ends after just one participant
Symptom relief Stopped earlyThe goal of this clinical trial is to adapt a mental health digital app to treat depression among head and neck cancer patients and survivors. Participants will download and use the digital mental health app for a 6-week period, and will complete related surveys.
Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Aug 01, 2026 00:00 UTC
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Massive mouth survey: 14,000 egyptians checked for oral lesions
Knowledge-focused Recruiting nowOral mucosal lesion represents a wide array of conditions. They may be the result of a local or systemic infection or trauma or the manifestations of a medical condition or neoplastic growth weather primary or metastatic or may be mistaken for a variation of a normal structure. T…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Healthy volunteers help unravel Drug's inner workings
Knowledge-focused CompletedThis study is to compare pharmacokinetics and safety profiles of single-administration of DA-5222 and co-administration of DA-5222-R1, DA-5222-R2 and DA-5222-R3 in healthy adult subjects in fed state
Phase 1 • Sponsor: Dong-A ST Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New drug AG-236 gets first human safety check
Knowledge-focused OngoingThe primary purpose of this study is to assess the safety and tolerability of a single dose of AG-236 administered subcutaneously in healthy participants.
Phase 1 • Sponsor: Agios Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC