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127005 trials found · Page 6091 of 6351
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Reading to babies: a surprising boost for tiny hearts and brains?
Knowledge-focused OngoingThe primary purpose of this pilot study is to specifically examine the effect of parental reading on the ANS of mother and neonate in the hospital setting. The investigators will examine the effect of live maternal-infant reading on typically developing infants to better understa…
Sponsor: Tulane University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Can schools sustain mental health support for students? new study explores how.
Knowledge-focused CompletedSchools need sustainable systems to improve climate and address student mental health. This study compares two sustainment models for Tier 2 mental health interventions within a Positive Behavioral Interventions and Support (PBIS) framework. Using a 2-arm, cluster randomized Type…
Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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French kids help set new standard for diagnosing speech disorders
Knowledge-focused CompletedThe velopharyngeal mechanisms (in particular the movements of the soft palate) is frequently affected by craniofacial anomalies such as cleft lip and palate. Nasofibroscopy is frequently used in clinical care to assess the velopharyngeal function because it allows for direct visu…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Could a cherry extract boost Runners' hearts?
Knowledge-focused CompletedGrowing body of evidence indicates favorable effects of Cornus mas (Cornelian cherry) supplements on cardiometabolic risk, including the improvement of HDL and glycemic indices, in line with vascular benefits. Experimental data feature bioactives from Cornelian cherry as potentia…
Sponsor: Wroclaw Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Cooling after cardiac arrest: did a new protocol reduce muscle relaxant use?
Knowledge-focused Stopped earlyThis will be a single center, retrospective, before-and-after, chart review of all patients undergoing TTM between June 1, 2017 and May 31, 2021 at MDMC. Initiation of the new TTM protocol occurred on April 22, 2019.
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Scientists adapt earthquake imaging to peek inside human bones
Knowledge-focused CompletedBlood circulation within bone is thought to have a key role in bone growth, in fracture healing and in the development of bone diseases like osteoporosis. Current medical imaging techniques such as conventional ultrasonography fail to detect blood circulation within bone. The inv…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:52 UTC
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New ultrasound measure may spot heart risk after chest surgery
Knowledge-focused CompletedIn postoperative thoracic surgery (lobe resection, pneumonectomy or wedge resection), cardiovascular complications are the most frequent (10 to 15%) with a significant morbi-mortality rate. Right ventricular (RV) dysfunction is a complication that can be multifactorial in post th…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Tiny study tests exercise during anorexia recovery – results uncertain
Knowledge-focused Stopped earlyPhysical hyperactivity is often associated to anorexia nervosa (AN). Data suggest common central pathways between hyperactivity and anorexia. Maintaining adapted physical activity (APA) during refeeding in AN is controversial. Many studies suggest beneficits of APA in AN on body …
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Blood samples from flu shots could shape Tomorrow's vaccines
Knowledge-focused CompletedThis was a phase IV, multi-center, open-label study. The study collected serum samples from children 6 months to less than (\<) 9 years of age who received Fluzone Quadrivalent vaccine and adults greater than or equal to (\>=) 65 years of age who received Fluzone High-Dose Quadri…
Phase 4 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:27 UTC
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Real-World study tracks how IBD patients choose between IV and injectable vedolizumab
Knowledge-focused CompletedVedolizumab is a medicine that helps to reduce sensitivity and pain in the digestive system for participants with UC or CD. In this study, adults with UC or CD will be treated with vedolizumab according to their clinic's standard practice. Participants will receive vedolizumab a…
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Heartburn drug tested against pancreatic cancer in early trial
Knowledge-focused Stopped earlyThe purpose of this study is to test the safety of high dose omeprazole and see what effects that it has on patients with exocrine pancreatic cancer.
Early phase 1 • Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Which interdental cleaner wins for gum health?
Disease control CompletedThe primary aim of this clinical study is to compare the effects of IDBs and RBICs on the removal of microbial dental plaque and gingival bleeding in patients with gingivitis. Secondarily, the study aims to assess participants' satisfaction and attitudes toward using these tools.
Sponsor: Bulent Ecevit University • Aim: Disease control
Last updated Jun 26, 2026 15:10 UTC
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Baby gut study: what you feed your infant shapes their bones
Knowledge-focused CompletedThe aim of the study is to establish the longitudinal microbiome and bone trajectories from birth to 3 years, and to evaluate the influence of nutrition on these trajectories.
Sponsor: Société des Produits Nestlé (SPN) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Tiny study aims to unravel proteinuria mystery in kidney transplant patients
Knowledge-focused OngoingCardiovascular disease remains one of the major cause of mortality in renal transplant recipients, with the rate of cardiac death 10-times higher than that of the general population. An independent association between post-transplant proteinuria and cardiovascular risk has been p…
Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Tiny study hopes to simplify muscle testing for rare muscle disease
Knowledge-focused CompletedIdiopathic inflammatory myopathies lead to important functional limitations resulting from the loss of muscle strength and endurance, especially in the hip and shoulder, which leads to a significant loss of quality of life for patients. The aim of this study is to correlate the "…
Sponsor: Federal University of Espirito Santo • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Ultrasound vs. reality: can scans predict tough gallbladder surgeries?
Knowledge-focused CompletedThis research is designed to correlate between intraoperative status of gallstone disease patients with their USG findings. The key question it aims to answer is: Does the ultrasonography predict laparoscopic cholecystectomy will be difficult?Further analysis will aim to reveal…
Sponsor: Nepal Medical College and Teaching Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Gum health tied to dental Know-How in new turkish study
Knowledge-focused CompletedThis observational cross-sectional study aimed to investigate the association between oral health literacy (OHL) and periodontal status among adult individuals attending Biruni University Faculty of Dentistry, Istanbul, Türkiye. A total of 108 adults were evaluated using the Turk…
Sponsor: Biruni University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Neck training plus pilates may boost balance in desk workers
Knowledge-focused CompletedThis study investigates the effects of Pilates reformer exercise combined with cervical sensorimotor training using laser-guided visual feedback on balance performance. Participants were randomly assigned to three groups: a combined training group, a Pilates-only group, and a con…
Sponsor: Ewha Womans University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Can your mindset predict how well you cope after prostate cancer treatment?
Knowledge-focused OngoingThis prospective single-group interventional study evaluates the relationship between sense of coherence (SOC), health-related quality of life (HRQL), and self-rated health (SRH) in patients with prostate cancer treated with radical radiotherapy. The study aims to identify factor…
Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Could a simple drug tweak metabolism in obesity?
Knowledge-focused CompletedThe aim of this study is to reduce fasting circulating BCAA concentrations in volunteers using Sodium Phenylbutyrate. In addition, we aim investigate the effect of BCAA lowering on fasting blood glucose levels, insulin sensitivity measures and muscle metabolism.
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC