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127005 trials found · Page 6052 of 6351
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App-Based study aims to improve chronic pain tracking
Knowledge-focused Stopped earlyMedtronic, Inc. is sponsoring the SENSE SCS clinical study, a prospective, multi-center, post-market, non-randomized, observational study with a hybrid decentralized model of execution, utilizing a mobile application for the collection of patient reported outcomes (PROs). The pur…
Sponsor: MedtronicNeuro • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Grocery gains: shopping bags as strength training?
Knowledge-focused CompletedWhat Is This Study About? To find out whether carrying heavy shopping bags twice a week can help adults not currently meeting physical activity strength guidelines improve muscle mass, strength, power, and endurance. What Can Be learnt? * Can carrying shopping bags help improve…
Sponsor: University of Glasgow • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Tablets before bed may disrupt kids' sleep, study finds
Knowledge-focused CompletedTo test the timing of evening tablet use on children's circadian phase and sleep (i.e., sleep onset and sleep duration) compared to no screen media use. To explore the effect of evening tablet use on children's inhibitory control and executive function.
Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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New 3D scan method could make dental implants last longer
Knowledge-focused CompletedQuantification and visualization the internal and marginal gaps by newer digital methods, such as the triple-scan protocol described by Borga Dönmez et al. (2024), employing 3D analysis software, offering a more objective and reproducible assessment.
Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New grid could make cancer scans sharper, safer
Knowledge-focused CompletedThis is Pilot study that investigates the CBCT(Cone beam computed tomography) image quality improvement provided by the 2D antiscatter grid technology. The primary objective is to assess the improvement in tissue visualization in an observer study, which will be conducted in a bl…
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Vaping alcohol: can E-Cigs fool breathalyzers?
Knowledge-focused CompletedThe purpose of this research study is to determine if ethanol-containing e-cigarettes impact ethanol breath, blood or oral fluid tests, field sobriety tests, or other tests of sobriety. Ethanol is a common part of e-cigarette liquids.
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Richmond study shines light on black Girls' strengths, not just struggles
Knowledge-focused CompletedThis study is to understand the quality of life of Black Girls in Richmond, Virginia, which includes generating a report about the status of Black girls in Richmond. Research or reports about the state of the girls are growing more common across the country in cities like Los Ang…
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Tooth decay study: do symptoms and cavity depth predict treatment success?
Knowledge-focused Recruiting nowThe goal of this prospective, observational clinical cohort study is to study the effect of the preoperative condition of the tooth on the outcome of partial removal of carious tissue in mature teeth in adults. The main questions the study aims to answer are: * Do preoperative s…
Sponsor: University of Helsinki • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Scientists probe cell power plants after burns
Knowledge-focused Recruiting nowThe goal of this observational study is to assess the impact of burn injury on cellular energetics in patients that have been admitted to the burn center at Arkansas Children's Hospital for burn care and require one or more procedures to clean, debride, and repair burn wounds wil…
Sponsor: Arkansas Children's Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New device tested for labia reduction in small study
Symptom relief CompletedLabiaplasty is a procedure aimed at reducing lax or loose skin in the labia majora and/or minora due to childbirth, trauma, aging, genetics, or congenital disease.
Sponsor: Apyx Medical • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Could a finger sensor replace the blood pressure cuff?
Knowledge-focused CompletedBackground: Blood pressure is one of the key markers of cardiovascular health. High blood pressure, also called hypertension, can increase the risk of heart disease or stroke. Monitoring a person s blood pressure continuously over a 24-hour period at home is the best way to diag…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New steerable wire aims to simplify brain aneurysm repair
Disease control Stopped earlyThe aim of the study is to assess the safe and successful use of the SmartGUIDE guidewire in neuro interventions and to compare to standard of care guidewires on the market.
Sponsor: Artiria Medical • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Could a Head-Zap gadget tame Alzheimer's agitation?
Symptom relief CompletedThe purpose of this study is to assess acceptability, and safety of providing tDCS to ADRD patients with behavioral symptoms and to assess the efficacy of tDCS for ADRD-related symptoms, mainly behavioral symptoms.
Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Drug interaction study reveals how common antifungal alters cancer medicine levels
Knowledge-focused CompletedThe main objective of this trial is to investigate the effect of multiple doses of the strong CYP3A inhibitor and recommended P-glycoprotein (P-gp) inhibitor itraconazole on the pharmacokinetics of a single dose of zongertinib in plasma following oral administration.
Phase 1 • Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Ancient needle vs heat: which warms your back better?
Knowledge-focused CompletedLow back pain is a common clinical condition, with up to 84% of adults experiencing varying degrees of low back pain. The most common form of low back pain is non-specific low back pain, which is often treated symptomatically in medicine due to its lack of etiology, which has man…
Sponsor: The Third Affiliated hospital of Zhejiang Chinese Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Probiotic study probes gut leakiness in healthy volunteers
Knowledge-focused CompletedThis study is being done to assess the effects of S. boulardii CNCM I-745 compared to placebo on impaired intestinal permeability, which is the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall into the rest of the body.
Early phase 1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Can a computer program help doctors decode clotting tests?
Knowledge-focused CompletedThe purpose of this study is to assess a novel rotational thromboelastometry (ROTEM®) interpretation software to determine whether its use improves the accuracy of clinician interpretation.
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Can a collagen patch improve gum healing after dental bone grafts?
Disease control Recruiting nowGuided bone regeneration (GBR) is a procedure used to increase the amount of bone volume in the jaw before placing a dental implant. It is needed when a lot of bone has been lost around the spot where a tooth has been lost or extracted. An incision is made, bone grafting materia…
Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New finger clip device tested for measuring dangerous low oxygen levels
Diagnosis CompletedThe aim of this study is to determine the accuracy of devices called pulse oximeters, which measure blood oxygen by shining light through fingers, ears or other skin, without requiring blood sampling. Study will be used with patients at rest.
Sponsor: Nihon Kohden • Aim: Diagnosis
Last updated Jun 26, 2026 16:37 UTC
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Scientists track prednisolone levels to improve dosing for inflammatory conditions
Knowledge-focused Recruiting nowThis is a pilot study to investigate serum prednisolone profiles in: * Patients on high doses of prednisolone for any inflammatory disorder, both in the acute and chronic setting. * Patients stepping up from or down to prednisolone therapy in association with a course of high do…
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC