New grid could make cancer scans sharper, safer

NCT ID NCT04565457

Completed Knowledge-focused Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether a special 2D antiscatter grid can improve the quality of cone-beam CT (CBCT) images used during radiation therapy for prostate, head and neck, and upper abdomen cancers. 43 participants received one extra CBCT scan with the grid, and researchers compared image clarity, artifacts, and contrast to standard scans. The goal was to see if the grid reduces image errors and improves tissue visibility, which could help doctors target tumors more precisely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 2D antiscatter grid (device)
What this could lead to: If successful, this technology could improve image clarity in CBCT scans, potentially leading to more accurate radiation therapy targeting.
What could go wrong: This is a small pilot study focused on image quality, not patient outcomes. The improvement may not translate to better treatment results or be adopted widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

digestive system cancer head and neck cancer Head and Neck Neoplasms prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK CANCERS PROSTATE CANCER UPPER ABDOMEN CANCERS

Contacts and locations

Locations

University of Colorado Hospital

Aurora, Colorado, 80045, United States
University of Florida Health Proton Therapy Institute

Jacksonville, Florida, 32206, United States

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