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127005 trials found · Page 6024 of 6351
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Dental study seeks best way to retract gums for digital impressions
Knowledge-focused CompletedThe study aims to identify which retraction method offers optimal balance between tissue displacement, scan clarity, and patient comfort, particularly in the esthetic zone, while avoiding the use of CBCT. Results will guide clinicians in selecting the most effective and minimally…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:22 UTC
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Oxygen mapping in the colon could unlock secrets of vascular lesions
Knowledge-focused Recruiting nowThe goal of this clinical trial is to evaluate oxygenation in the colon in people with acquired vascular abnormalities in the proximal colon.
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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New eye scanner aims to sharpen view of retinal disease
Knowledge-focused CompletedThe primary objective is to collect images on the P200TxE device in diseased eyes.
Sponsor: Optos, PLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Can report cards and stories nudge doctors to better heart care?
Knowledge-focused CompletedThis is a prospective randomized clinical trial evaluating how two behaviorally-informed interventions (i.e., monthly report card and storyboard interventions) impact physician behavior, with the goal of closing care gaps in preventive care and disease management. In particular,…
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Dental study tests which elastic works best for tooth movement
Knowledge-focused CompletedThis clinical study aimed to evaluate the effectiveness of Elastics and Elastic chains in maxillary canine retraction. Participants of this study were patients undergoing maxillary canine retraction after first premolar extraction. The study aimed to determine an effective method…
Sponsor: Sana'a University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:43 UTC
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New antibiotic cocktail takes first step in human safety trial
Knowledge-focused CompletedA Phase 1, Open-Label, Drug-drug Interaction, and Randomized, Double-blind, Controlled, Multiple-dose Pharmacokinetics and Safety Study of Xeruborbactam Oral Prodrug (QPX7831) in Combination with Ceftibuten in Healthy Adult Participants
Phase 1 • Sponsor: Qpex Biopharma, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Brain bleed data hunt aims to improve emergency care
Knowledge-focused Recruiting nowThis retrospective data repository will serve as a means to aggregate and analyze standard surgical interventions and Middle Meningeal Arteryembolization as suitable treatment options for Acute Subdural Hematoma.
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Shower sooner? new study tests best time to bathe after bone surgery
Knowledge-focused Recruiting nowThis is a single center randomized control trial assessing the effect of early versus delayed bathing on orthopaedic surgical wounds in patients undergoing surgical treatment of fractures. Patients will be recruited by screening all patients undergoing surgical treatment for frac…
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Botox study shows promise for smoothing upper face wrinkles
Symptom relief CompletedThe goal of this observational study is to learn about the safety, tolerability, and effectiveness of Letibotulinumtoxin A for the holistic treatment of the upper face in adults under 75 years old with moderate to severe upper facial lines, including glabellar lines, forehead lin…
Sponsor: Yuvell • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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App-Based knee pain therapy tested against In-Person care
Symptom relief Stopped earlyThe purpose of this clinical study is to demonstrate that after six weeks of at home exercise, 3 times per week with SimpleTherapy, participants with clinical indications of knee OA will on average have improved outcomes noninferior than traditionally prescribed physical therapy …
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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New diabetes drug passes first safety check in healthy men
Knowledge-focused CompletedThis study is testing a new study medicine which may be used to treat people with type 2 diabetes. NNC0650-0013 is a new medicine, which cannot be prescribed by doctors. The purpose of the study is to see if the new study medicine is safe, and how it works in participants body. P…
Phase 1 • Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Scientists map Brain's emotion and time tracker
Knowledge-focused Recruiting nowTo support optimal behavior in daily life, goals and responses following emotional events should ideally incorporate not only the valence and intensity of prior emotional episodes but also their temporal features, such as the relative duration of positive vs. negative attributes.…
Sponsor: University of California, Santa Barbara • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Spine adjustments tested for Post-Concussion relief
Knowledge-focused Stopped earlyThis proof-of-concept trial will explore the effects of manual chiropractic adjustments on nervous system function in individuals with post-concussion syndrome. This study will aim to recruit 10 individuals to receive 6 weeks of chiropractic care with 3 assessment periods. The pa…
Sponsor: Life University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Sleepless nights may amplify pain, study suggests
Knowledge-focused CompletedThis interventional study aims to test the effects of sleep disruption on pain sensitivity and biomechanics in healthy individuals during experimental knee and shoulder pain. The main question the study aims to answer is: 1\) Does sleep fragmentation increase experimental knee a…
Sponsor: Aalborg University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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New dermal filler tested for wrinkle reduction
Symptom relief CompletedThis study designed to evaluate the safety and performance of RefillHA Volume, a dermal filler for facial soft tissue augmentation and correction of facial wrinkles and folds in routine clinical setting.
Sponsor: Glyance • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Your personality could be key to sticking with CML treatment
Knowledge-focused Recruiting nowThis is an observational pilot study to examine the association between a patient's personality and adherence to tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia.
Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New dialysis device for Wilson's disease tested but trial stopped early
Disease control Stopped earlyThe goal of this clinical trial is to test the MEX-CD1 hemodialysis medical device in patients suffering from Wilson's Disease. The main questions it aims to answer are: * Does the device work as expected by removing the excess of free copper from the blood? * Is the device safe…
Sponsor: Mexbrain • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Tiny study sucks up wound goo to unlock healing secrets
Knowledge-focused CompletedThe observational longitudinal study will collect wound exudate from twenty patients with venous leg ulcers. Wound exudate samples are collected using twenty-four-hour collection with polyurethane foam, bandages and the NovaSwab method. Each patient is seen four times where wound…
Sponsor: Bispebjerg Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Eye imaging showdown: MRI vs ultrasound
Knowledge-focused Recruiting nowD0: inclusion visit * information * Realization of the ocular ultrasound (care) * Collection of consent * Realization of high resolution MRI with injection of contrast product (duration of 30 minutes) For the realization of the MRI, the contrast product used is the gadobutrol. T…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Egg study reveals Age-Based differences in HDL and immune response
Knowledge-focused CompletedThe goal of this intervention study is to determine whether consumption of different fractions of chicken eggs, including egg whites, egg yolks, and whole eggs, confer different changes in markers of HDL function and T cell profiles in younger vs. older men and women. The study w…
Sponsor: University of Connecticut • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC