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127005 trials found · Page 5984 of 6351
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PET scans shed light on Drug's effect in Crohn's gut
Knowledge-focused CompletedThe purpose of this study is to measure the changes in intestinal uptake of radioligand \[11C\]AZ14132516 following multiple doses of AZD7798 in participants with Crohn's disease.
Phase 1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Study reveals best way to insert IVs to reduce needle movement
Knowledge-focused CompletedThis proposed study aims to fill this gap by investigating whether needle tip movement during catheter advancement is affected by whether the individual performing the insertion pushes the catheter off the needle themselves or if it is done by another person.
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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New obesity drug formulations tested in small study
Knowledge-focused CompletedThis study will look into a new study medicine called NNC0519-0130 to improve the treatment option for people living with excess body weight or type 2 diabetes or both. The purpose of this study is to compare the amount of NNC0519-0130 in the blood of participants who have excess…
Phase 1 • Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Can a 5-Question survey improve urinary incontinence care?
Knowledge-focused Recruiting nowPRAFAB assesses both the objective and subjective aspects of urinary incontinence. While differing from other questionnaires in this respect, it consists of only five questions. Today, there is a need for multidimensional and easy-to-use scales that can assess the effects of inco…
Sponsor: Afyonkarahisar Health Sciences University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Text or portal: which gets parents access to Kids' health records faster?
Knowledge-focused Recruiting nowThe goal of this randomized controlled trial is to assess the extent to which different modes of contacting parents who have not yet enabled to access to their children's medical records will result in greater proxy access. The main questions the study aims to answer are: * will…
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New tool could help turkish Parkinson's patients avoid falls
Knowledge-focused CompletedThe aim of this study is to adapt the Dresden Falls Questionnaire scale (DREFAQ) to Turkish society and to make its validity and reliability in Turkish. The DREFAQ) scale developed by Frank, Anika, et al assesses falls in patients with Parkinson. It has 5 questions. This study wi…
Sponsor: Istanbul Medeniyet University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:34 UTC
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Exercise study for advanced lung cancer falls short
Symptom relief Stopped earlyThe purpose of this study is to examine how a multimodality (having or using a variety of methods to do something) exercise intervention may improve survival, function, and quality of life in participants with advanced lung cancer.
Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Can a short workout reveal why we lose balance as we age?
Knowledge-focused Recruiting nowThis is a single-arm, two-visit, non-randomized, cross sectional study identified as an intervention due to the use of a single bout of aerobic exercise to assess cerebrovascular function under the NIH rules. This study is not masked and its primary purpose is to develop a basic …
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Heart-Kidney drug trial halted early – what happened?
Disease control Stopped earlyThe present study is designed to test the effect of AZD3427 on renal perfusion in participants with heart failure and reduced eGFR (30 to 90 mL/min/1.73m2).
Phase 1 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Mood over muscles: study tests if feeling good gets you moving
Knowledge-focused CompletedThe goal of this study is to assess the effects of an exercise-related video on exercise motivation and adherence. Specifically, the researchers are studying whether an exercise-for-mood video increase levels of exercise motivation as compared to an exercise-for-fitness video.
Sponsor: Boston University Charles River Campus • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New study compares high-tech gum cleaning to traditional methods
Knowledge-focused CompletedAIM: This prospective clinical study aimed to evaluate the efficacy of two distinct non-surgical periodontal therapy modalities in patients diagnosed with Stage 1 and Stage 2 periodontitis. METHOD: The study comprised 80 nonsmoking, systemically healthy volunteers. Patients were…
Sponsor: Selcen Ozcan Bulut • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Swiss study probes ICU Workers' views on brain death and donation
Knowledge-focused CompletedThe study aims to gather information regarding the individual perceptions, opinions, beliefs, and conceptual understanding of healthcare professionals working in the intensive care units at the University Hospital Basel, the Cantonal Hospital Aarau and the Cantonal Hospital Basel…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New study aims to sharpen breast cancer detection tech
Knowledge-focused OngoingThis is a prospective, multi-center image case collection study to acquire de-identified contrast-enhanced breast images on a mammography device to support continuing software technology development. Eligible subjects include women at least 35 years old with a suspicious finding …
Sponsor: Hologic, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Promising c. diff drug trial halted after just 3 patients
Disease control Stopped earlyThis is a multi-center, open-label study to investigate the safety, tolerability, pharmacokinetics (PK) and efficacy of REC-3964 (doses of either 250 mg or 500 mg PO every 12 hours) for the reduction of Clostridioides difficile infection (CDI).
Phase 2 • Sponsor: Recursion Pharmaceuticals Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Hand surgery foil study halted early – only 15 patients enrolled
Prevention Stopped earlySingle arm study to evaluate the safety and performance of Genta-Foil resorb® for the prevention of tissue adhesions
Sponsor: Advanced Medical Solutions Ltd. • Aim: Prevention
Last updated Jun 27, 2026 07:58 UTC
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Virtual reality study reveals Culture's hidden influence on brain and movement
Knowledge-focused CompletedThis observational study examined how long-term cultural background is associated with differences in cognitive and motor learning within a virtual reality environment. Forty-three healthy university students participated in four days of standardized assessment procedures involvi…
Sponsor: Bahçeşehir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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No new drug, just data: large european study to map myelofibrosis outcomes
Knowledge-focused Recruiting nowMulticenter retrospective and prospective European observational study. At each site, all consecutive patients with a 2016- or 2022 World Health Organization (WHO) confirmed diagnosis of myelofibrosis (MF) established from 01/01/2018 to 31/12/2027 will be enrolled into the study.…
Sponsor: FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Diabetes and the mind: new study probes hidden links
Knowledge-focused Recruiting nowThe aim of this study is to examine the relationship between motor imagery skills, body awareness and cognitive functions in individuals with Type 2 Diabetes mellitus.
Sponsor: Kutahya Health Sciences University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Patients hold their own oxygen mask in new anesthesia study
Knowledge-focused CompletedThe aim of this research would be to determine the efficacy and effects of preoxygenation when performed by the patient (mask held by the patient). This is the concept of "self-preoxygenation".
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:44 UTC
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Big data vs. clinical trials: can insurance records match gold-standard results?
Knowledge-focused CompletedInvestigators are building an empirical evidence base for real-world data through large-scale replication of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real-world data analyses can be conducted with confidence and h…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC