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127005 trials found · Page 5964 of 6351
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Bipolar disorder study digs into pain and sleep patterns
Knowledge-focused CompletedBipolar disorder (BD) is a complex condition characterized by recurrence of mania, hypomania, and depression. It is characterized by changes in daily life activities, sleep status, focus problems, and cognitive fluctuations. The mortality rate due to suicide and cardiovascular di…
Sponsor: Kutahya Health Sciences University • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Scientists scan brains during sleep to unlock learning secrets
Knowledge-focused CompletedA growing body of evidence suggests that sleep facilitates and is beneficial to perceptual learning. However, the underlying mechanism of this facilitatory action is largely unknown. One must know what type of processing occurs during sleep to clarify the mechanism of sleep facil…
Sponsor: Brown University • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC
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Small study seeks best dose of anesthesia booster for joint surgery
Knowledge-focused CompletedDetermine ED50 dexmedetomidine adjuvant that can provide spinal anesthetic sensory blockade duration of 200 minutes on knee and pelvis surgery with up-and-down method.
Sponsor: Indonesia University • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:30 UTC
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Study reveals best position for blood flow restriction exercise
Knowledge-focused CompletedTo test the effect of limb occlusion pressure attainment in the supine, seated, and standing position on exercise performance, vascular physiology, and muscle.
Sponsor: Teri Herberger • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Microscope vs. loupes: which makes root canals faster?
Knowledge-focused CompletedThe aim of this observational study is to compare the treatment durations of different stages of routine root canal therapy performed on maxillary molar teeth using direct vision, magnification loupes, and a dental operating microscope. The primary question the study seeks to an…
Sponsor: Uşak University • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Which cut hurts less? study tests incision direction for port placement
Symptom relief CompletedThe aim of the study is to assess whether the direction of skin incision affects pain within the first 24 hours, patient comfort 7 days after the procedure, procedure time, and the occurrence of early complications related to vascular port implantation.
Sponsor: Jagiellonian University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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New mouthwash combo shows promise for gum disease
Disease control CompletedPatients were instructed to use 2 different mouthwashes after performing professional tooth cleaning. The effect of each of the 2 mouthwashes was detected.
Phase 3 • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 08:14 UTC
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New turkish scale helps measure breathing trouble in silent patients
Knowledge-focused CompletedDyspnea is a subjective experience influenced by physiological, cognitive, behavioral, and sociocultural factors. While self-reported scales are commonly used to assess dyspnea severity, they are unsuitable for patients unable to communicate, such as those with cognitive impairme…
Sponsor: Istinye University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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3D printed retainers could beat Old-School wires in new trial
Knowledge-focused OngoingAlthough there are many studies in the literature concerning with methods of bonding of mandibular retainers whether directly or indirectly, there is a very limited evidence regarding their chair side time and bond failure. Also there are scarce data on 3D printed fixed mandibula…
Sponsor: Raghda Alaa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Eye drop showdown: which artificial tear sharpens vision best?
Knowledge-focused CompletedThis study evaluates the immediate effects of two types of artificial tear formulations on corneal aberrations in a healthy population. The interventions include a lipid-based formulation containing mineral oil and hydroxypropyl guar, and a non-lipid formulation containing hydrox…
Phase 4 • Sponsor: University of Seville • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Green moms: how Eco-Friendly breastfeeding boosts bonding
Knowledge-focused CompletedThis research aimed to identify sustainable breastfeeding practices and green mothers' initiatives to develop a strong mother-child bond.
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Liver function and drug processing: a closer look at divarasib
Knowledge-focused CompletedThis is a phase 1, open-label, single-dose, parallel-cohort study to determine the pharmacokinetics (PK) of divarasib in healthy participants and participants with varying degrees of hepatic impairment, as defined by Child-Pugh classification.
Phase 1 • Sponsor: Genentech, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Eco-Education may boost breastfeeding, small study suggests
Knowledge-focused CompletedThis study aimed to evaluate the impact of carbon footprint education on breastfeeding practices among pregnant women.
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Supplement study sees if testosterone gets a boost
Knowledge-focused CompletedThe primary purpose of this study is to investigate the effects of geranylgeraniol (GG) supplementation on testosterone levels in middle-aged (40 to 65 years) healthy men and women. The research team hypothesizes that geranylgeraniol (GG) supplementation will enhance testosteron…
Sponsor: Designs for Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Tooth infection shrinks jaw muscle, ultrasound reveals
Knowledge-focused OngoingIn teeth that remain decayed for a long time, the muscles in that area atrophy because the patient cannot use the decayed area much. As a result, muscle length and mass decrease. To compare the amount of this reduction before and after treatment with ultrasound and to treat accor…
Sponsor: Harran University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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New program aims to fight fatigue in kidney disease patients
Symptom relief CompletedIn this pilot trial, investigators will pilot test a cognitive behavioral intervention for acceptability and proof of concept for a larger future trial to be submitted for federal funding. This is a one-group design with qualitative and quantitative data collection integrated int…
Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Chewing gum reveals how dental treatment boosts Kids' bite power
Knowledge-focused CompletedThis prospective clinical study aimed to evaluate the effects of dental treatment on masticatory performance and food preferences in children during the mixed dentition period. A total of 100 children aged 6 to 9 years were included and categorized into three groups based on the …
Sponsor: TC Erciyes University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Dental students vs. experts: who scores root canals better?
Knowledge-focused CompletedThis prospective cohort study evaluates dental students' self-assessment of clinical endodontic performance and compares it with independent evaluations conducted in a dental education clinical setting. Endodontic treatments are performed by undergraduate dental students using tw…
Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Spinal anesthesia study reveals key insights on urine output
Knowledge-focused CompletedThis clinical trial investigates the relationship between urine output and mean arterial pressure (MAP) during spinal anesthesia. The study aims to validate observations from animal models in humans by concurrently measuring hemoglobin levels, MAP, and urine output, focusing on t…
Sponsor: Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Brain fog and obesity: new study links thinking skills to physical fitness
Knowledge-focused Recruiting nowThis study was planned to examine the effect of executive function problems on physical performance and general well-being in obese individuals.
Sponsor: Kutahya Health Sciences University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC