Small study seeks best dose of anesthesia booster for joint surgery

NCT ID NCT07144215

Completed Knowledge-focused Sponsor: Indonesia University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study with 40 adults undergoing hip or knee surgery aimed to find the most effective dose of dexmedetomidine when added to standard spinal anesthesia. Researchers tested doses from 3 to 6 micrograms to see which one made the numbness last at least 200 minutes. The goal is to improve pain control during and after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexmedetomidine
What this could lead to: If successful, this could help doctors choose the right dose of dexmedetomidine to make spinal anesthesia last longer during hip and knee surgery.
What could go wrong: This is a small, early-phase study with only 40 participants, so results may not apply to everyone. The main risks include low blood pressure, slow heart rate, and nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE SURGERY PELVIC SURGERY SPINAL ANESHTESIA

Contacts and locations

Locations

RSUPN Cipto Mangunkusumo

Jakarta Pusat, Jakarta Special Capital Region, 10430, Indonesia

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