Small study seeks best dose of anesthesia booster for joint surgery
NCT ID NCT07144215
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study with 40 adults undergoing hip or knee surgery aimed to find the most effective dose of dexmedetomidine when added to standard spinal anesthesia. Researchers tested doses from 3 to 6 micrograms to see which one made the numbness last at least 200 minutes. The goal is to improve pain control during and after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine
What this could lead to
If successful, this could help doctors choose the right dose of dexmedetomidine to make spinal anesthesia last longer during hip and knee surgery.
What could go wrong
This is a small, early-phase study with only 40 participants, so results may not apply to everyone. The main risks include low blood pressure, slow heart rate, and nausea.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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RSUPN Cipto Mangunkusumo
Jakarta Pusat, Jakarta Special Capital Region, 10430, Indonesia