Eye drop showdown: which artificial tear sharpens vision best?

NCT ID NCT06784661

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two artificial tear formulations in 40 healthy adults aged 18-35. One type contains lipids (mineral oil and hydroxypropyl guar) to mimic natural tears, while the other is a simpler non-lipid drop. Researchers measured changes in corneal aberrations (tiny imperfections affecting vision) before and 15 minutes after a single drop in each eye. The goal is to see which formulation better stabilizes the tear film and improves optical quality.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

artificial tears (lipid-based: mineral oil and hydroxypropyl guar; non-lipid: hydroxypropyl guar)

What this could lead to

If it works, this could help eye doctors choose the best artificial tear type for improving vision quality in people with dry eyes.

What could go wrong

This is a small, completed study in healthy people, not patients. The effects are measured only 15 minutes after a single drop, so long-term benefits are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Corneal Wavefront Aberration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ISEC Lisboa

    Lisbon, Portugal