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116076 trials found · Page 5741 of 5804
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New drug BI 3006337 passes early safety check in healthy volunteers
Knowledge-focused CompletedThe main objectives of this trial are to investigate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of BI 3006337 in healthy male subjects following s.c. administration of single rising doses and multiple doses over 6 weeks.
Phase: PHASE1 • Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Newborn bedtime routine study: is it doable for parents?
Knowledge-focused CompletedThe purpose of this study is to assess, via caregiver questionnaire, the acceptability and feasibility of implementing a bedtime routine for newborns.
Phase: NA • Sponsor: Johnson & Johnson Consumer Inc. (J&JCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Where you inject matters: new study tests insulin at three sites
Knowledge-focused CompletedThis open-label, randomized, three-period crossover, 8-hour hyperinsulinemic-euglycemic clamp study will compare the pharmacokinetic and pharmacodynamic profiles of THDB0206 after single subcutaneous administration at different injection sites in healthy Chinese adults.
Phase: PHASE1 • Sponsor: Tonghua Dongbao Pharmaceutical Co.,Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Kidney cancer surgery heart risk study pulled before starting
Knowledge-focused TerminatedKidney removal for cancer (nephrectomy) is a major operation. People can develop heart complications during or after surgery, especially if they are older or already have heart disease. One form of heart damage is called myocardial injury (MINS). This can be detected with a simpl…
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:46 UTC
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Neck disc study cancelled before it began
Knowledge-focused TerminatedThis is a real world data collection observational study at a single site. There are both prospective and retrospective cohorts. The study will examine the safety and effectiveness of the Synergy cervical disc system in patients with degenerative cervical disc disease.
Sponsor: Synergy Spine Solutions • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New pill 83-0060 passes first safety check in healthy volunteers
Knowledge-focused CompletedThis is a clinical study aiming to assess pharmacokinetics, pharmacodynamics and preliminary efficacy of 83-0060 in Healthy Volunteers
Phase: PHASE1 • Sponsor: Traws Pharma, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Tiny study on blood flow cuffs for shoulder injuries ends early
Symptom relief TerminatedAtrophy and weakness of the shoulder are a common problem following treatment of a number of shoulder and elbow pathologies. Even with relatively short periods of reduced activity, the magnitude of muscle loss can be quite substantial.
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Thyroid cancer Drug's side effect on body mass measured in small study
Knowledge-focused Completedinvestigation of body composition
Sponsor: University of Pisa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New drug ZE63-0302 tested in healthy volunteers for first time
Knowledge-focused CompletedA first-in-human study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple ascending doses of ZE63-0302 administered orally in healthy volunteers.
Phase: PHASE1 • Sponsor: Eilean Therapeutics • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Why do pregnant women refuse to join a pre-eclampsia trial? new study investigates.
Knowledge-focused CompletedThe main objective is to assess whether there are factors associated with women's refusal to participate in a randomized clinical trial involving first-trimester screening for pre-eclampsia. The secondary objective is to qualitatively evaluate the reasons for acceptance and refus…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:22 UTC
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Kangaroo care: bonding boost or bust?
Knowledge-focused TerminatedThe Kangaroo Unit (UK) takes care of newborns requiring special care or monitoring for a pathology whose clinical situation is stable and whose prognosis is favorable. In order to avoid separating mother and child, these units were created with a care pathway somewhere between th…
Sponsor: Centre Hospitalier Régional Metz-Thionville • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New anesthesia drug checked for heart risks in healthy volunteers
Knowledge-focused CompletedTo assess the effects of a single IV bolus of HSK3486 single dose on cardiac repolarization (QTc interval of the electrocardiogram, and to evaluate the safety and tolerability of a single IV bolus of HSK3486 in healthy subjects
Phase: PHASE1 • Sponsor: Haisco-USA Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New drug PORT-77 tested in humans for first time
Knowledge-focused CompletedA First-in-Human 2-part, randomized, double-blind, placebo-controlled, single ascending dose, multiple ascending dose, and food effect, investigation of the administration of PORT-77 in healthy adult participants.
Phase: PHASE1 • Sponsor: Portal Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Ashwagandha safety check in seniors: small study ends early
Knowledge-focused TerminatedThis study will measure the oral bioavailability and pharmacokinetics of known compounds from a standardized Withania somnifera botanical dietary supplement in healthy older adults.
Phase: EARLY_PHASE1 • Sponsor: Oregon Health and Science University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Heart drug study cancelled before it began
Knowledge-focused TerminatedCardiovascular disease (CVD) represents the leading cause of death worldwide. While medications, such as statins, significantly reduce atherosclerotic CVD (ASCVD) risk by lowering low density lipoprotein levels, they may also have pleiotropic effects on inflammation. The immunomo…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Baby massage class boosts student Know-How, study finds
Knowledge-focused CompletedThe goal of this clinical trial was to learn whether baby massage training could improve midwifery students' knowledge about baby massage. The study focused on students in their third and fourth years who had already completed child health and neonatal care courses. The main que…
Phase: NA • Sponsor: Ataturk University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Promising ITP drug trial pulled before it even started
Disease control TerminatedThis is an open-label, multicenter study to evaluate the safety, tolerability, and efficacy of HMPL-523 in adult subjects with ITP.
Phase: PHASE1 • Sponsor: Hutchmed • Aim: Disease control
Last updated Jun 26, 2026 18:23 UTC
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Fat emulsion could be new weapon against pesticide poisoning
Disease control TerminatedAim of the study: To assess the role of intralipid emulsion in the acute man-agement of organophosphorus toxicity and its benefits in de-creasing mortality rates among victims.
Phase: PHASE2, PHASE3 • Sponsor: Amani Hassan Abdel-Wahab • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Tiny cancer study halted after just one patient
Knowledge-focused TerminatedThis phase I trial studies on how the PEOX-based polymer encapsulated paclitaxel FID-007 (FID-007) affects the immune cells around the tumor patients with head and neck squamous cell carcinoma. The active drug in FID-007 is paclitaxel, an established chemotherapy drug that has be…
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:26 UTC
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Could your Diet's antioxidants protect your metabolism? study digs into national data
Knowledge-focused TerminatedThis cross-sectional study draws on data from the National Health and Nutrition Examination Survey (NHANES) database. The primary objective is to investigate the associations between the Composite Dietary Antioxidant Index (CDAI) and overweight/obesity, as well as the related met…
Sponsor: University-Town Hospital of Chongqing Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC