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The aim of this study is to determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of bemarituzimab given in combination with a fixed dose of bevacizumab and to assess the clinical activity of the proposed combination bemarituzumab and bevacizumab in 3 par…

This study is to assess the mass balance of oral ABBV-1354 in healthy adult male participants.

The aim of this study is to develop a dataset with reference body composition measurements using criterion methods. This dataset will be used to develop new protocols to study patients with cancer. Obtaining measurements of sodium bromide (NaBr), deuterium dilution (D2O), and D3-…

this study will compare two warm-up methods before cardiopulmonary exercise testing (CPET) in recreationally active young adults. Participants will complete treadmill walking or TRX suspension warm-up, followed by a treadmill exercise test to exhaustion. The investigators to dete…

The primary objective of the study is to describe the recovery and survival of pathogen-reduced (PR) red blood cells (RBCs) prepared and stored with the INTERCEPT Blood System for RBCs® (hereafter referred to as INTERCEPT RBCs) in patients with sickle cell disease (SCD) undergoin…

participants are randomized to a study arm that measures intention to perform a health related behavior and follows up to measure behavior

The goal of this open label case series is to learn about the feasibility of conducting a future randomised controlled trial to evaluate how well the Perinatal SMILES intervention works in improving post-cesarean mood in low-income women. The main questions it aims to answer are…

Fenice has proposed a new indicator to measure the level of crowding in the ER. The aim of this study is to evaluate, in a national multicenter context, the degree of agreement between the Fenice indicator and the perception of crowding of the ER operators and to compare this agr…

This observational, cross-sectional laboratory study at Hacettepe University will examine surface EMG activation of the latissimus dorsi during resisted, dynamic shoulder extension performed at three shoulder flexion angles (30°,60°, 90°, 120°). The primary objective is to quanti…

This is a single-center, single-arm observational study in which the investigators aim to develop an advanced motion control system for head stabilization in patients undergoing whole brain radiation therapy.

This is a phase I study in Chinese healthy adult volunteer participants. It aims to evaluate the safety, tolerability, PK profile and immunogenicity of a single dose of SM17 SC in healthy Chinese adult participants. It also aims to evaluate the bioavailability of SM17 SC compared…

The purpose of this stud is to evaluate the drug-drug interaction between IY001 and IY002 in adult males.

Study to demonstrate pharmacokinetic and pharmacodynamic similarity between NKF-INS(L), US-Humalog®, and EU-Humalog®

For this study, the study medicine has been specially prepared to contain radiolabeled carbon \[14C\]. \[14C\] is a naturally occurring radioactive form of the element carbon. Adding a low dose of radiation to the study medicine does not change how the medicine works but helps to…

ABSTRACT Aim: This study aimed to evaluate the effect of the flipped classroom model on students' academic achievement and learning motivation. Methods: This randomized controlled study was conducted between October 13 and October 31, 2025, with midwifery students at a state …

This single-visit, laboratory study will quantify latissimus dorsi activation during standardized band/body-weight exercises commonly used in rehabilitation (e.g., standing bent-over row, inferior glide, seated press-up, body-lifting). Healthy, physically active adults (18-40 y; …

Previous research has demonstrated the effectiveness of AFFRONEYE® / CROCUVIS+® dietary supplement, based on saffron extract, in the proper functioning of visual health, for example, against the development of glaucoma. The main objective of this study is to compare the results o…

This study aims to examine the effects of marketing claims on alcoholic beverage packaging on alcohol consumers' perceptions and intentions. Participants will be randomized to view three images of alcoholic beverages (beer, hard seltzer, flavored malt beverage) with one of three …

This study aims to validate the Ventriject Seismofit device by comparing VO2 Max obtained via the Seismofit and traditional Cardiopulmonary Exercise Testing.

The primary objective of this study is to explore perceptions and understanding of different menu label designs related to sustainability and environmental harm. Participants will be randomized to view a fast-food menu featuring one of seven labeling conditions and then will answ…