Botox tested as a remedy for facial flushing

NCT ID NCT02216838

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This study investigates whether injections of botulinum toxin A (Botox) can treat persistent facial flushing. In a split-face design, each participant receives Botox on one side of the face and a saline placebo on the other, allowing direct comparison. The trial enrolls 16 adults aged 18 to 65 with ongoing facial flushing and measures changes using a spectrophotometer. As a pilot study, it aims to see if this approach is worth studying further.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

botulinum toxin A (Botox)

What this could lead to

If effective, Botox could offer a new option for people bothered by persistent facial redness.

What could go wrong

This is a very small pilot study with only 16 people, so results may not apply broadly. Botox injections carry risks like bruising or temporary muscle weakness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Blushing

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Northwestern University Feinberg School of Medicine, Department of Dermatology

    Chicago, Illinois, 60611, United States