Love hormone nasal spray tested for borderline personality disorder trust issues
NCT ID NCT02225600
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study looks at whether a nasal spray of oxytocin, sometimes called the 'love hormone,' can improve trust and cooperation in people with borderline personality disorder (BPD). About 40 participants (some with BPD, some healthy) will play a trust game after receiving either oxytocin or a placebo. The goal is to see if oxytocin changes behavior and brain activity related to social interactions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oxytocin (nasal spray)
What this could lead to
If successful, this could point toward a better understanding of social difficulties in borderline personality disorder and whether oxytocin might help.
What could go wrong
This is a very small, early pilot study that is currently suspended. Results may not apply to real-world settings, and oxytocin's effects on social behavior are still uncertain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States