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This clinical trial aims to evaluate the efficacy of holistic medicine treatments for unmarried women ("Bachelorettes") residing on U.S. Tribal Lands or in the State of Alaska who have been clinically diagnosed with uterine fibroids. The study will assess both primary and seconda…

This study aims to investigate the effects of visual, auditory, and motor dual-task conditions on chewing performance in individuals with multiple sclerosis, compared with healthy controls.

This study aims to assess the safety of ARGX-124 in healthy adults. Another aim is to measure the amount of ARGX-124 in the blood over time to learn how it acts and moves in the body and how the immune system responds to it. Participants will remain in the study for up to approxi…

This open-label study will evaluate the effect of food on the bioavailability of a single dose of 4-MUST, tablets, 128 mg. Additionally, the study will assess the pharmacokinetics, safety, and tolerability of 4-MUST, tablets, 128 mg following both single and multiple oral dose ad…

A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Doses of MT-251 in Healthy Participants

To evaluate the pharmacokinetic interactions of AD-231A, AD-231B, and AD-231C in healthy adult volunteers.

This study is aimed to evaluate the effect of food on pharmacokinetics of QLS1410 in healthy Chinese adults.

How does one know what to look at in a scene? Imagine a "Where's Waldo" game - it's challenging to find Waldo because there are many 'salient' locations in the picture, each vying for one's attention. One can only attend to a small location on the picture at a given moment, so to…

The goal of this study is to find out how BI 1584862 moves through and exits the body of healthy men. To do this, BI 1584862 is labelled using radioactive carbon (C-14) and using a non-radioactive, naturally occurring, stable isotope (C-13). The study will measure how much of the…

The purpose of this study is to evaluate the safety and efficacy of a 3D-printed ingestible pill designed to sample microbiota from the GI tract, focusing on the ability to collect data also from the small intestine. The study also aims to assess ease of use and transit time.

13 weeks, open-label, daily disposable contact lens dispensing study.

The goal of this clinical study is to learn how different head-of-bed positions affect lung movement during breathing in healthy adults. Researchers want to understand whether raising the head of the bed changes how the lungs move, which may help guide patient positioning in emer…

The CBCT-based radiographic evaluation will be used to identify, classify, and measure the anatomical parameters of the GPC and maxillary sinus. These data will serve as a pre-surgical diagnostic guide for clinicians when performing procedures involving the posterior maxilla.

The primary objective of this study is to quantify the relationship between palatal morphology-including vault height, angle, width, and palatal bone thickness-and the dimensions and position of the greater palatine canal (GPC) and foramen (GPF). Secondary objectives include eval…

The overall objective of this pilot study is to establish the feasibility and methodological validity of using high-density surface electromyography to characterize motor unit behavior of the quadriceps under thermoneutral and locally cooled conditions, and to generate preliminar…

This study is a single-center, open-label, multiple-dose trial in healthy participants. The primary purpose of this study is to assess the adhesion of TK-254RX. Secondary purposes are to assess the safety of TK-254RX and the residual amount of the patch.

The main objective of this trial is to evaluate the pharmacokinetics of two evolocumab drug products in healthy participants.

To assess feasibility of a a trial investigation postoperative patient-reported quality of recovery after total knee arthroplasty (TKA) with periarticular joint injection (PAI) ± single shot adductor canal block with or without adductor canal catheter infusion.

Laparoscopic cholecystectomy and the associated pneumoperitoneum can impair diaphragmatic mechanics and reduce postoperative oxygenation. This prospective observational study aims to evaluate perioperative changes in diaphragmatic excursion measured by ultrasonography and to inve…

Climate change is a major global problem threatening individual health, public health, and health systems. Climate change poses a significant global threat to social and environmental health determinants, such as the disruption of food systems, the spread of climate-sensitive dis…