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116076 trials found · Page 5641 of 5804
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Scientists hunt for dementia genes in 2,256-Person study
Knowledge-focused CompletedPatients with different types of dementia will be recruited and evaluated in national hospital departments for their usual neurological follow-ups. A blood sample will be proposed in the field of this research project, and the biological material will be stored at the DNA and Cel…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Alpha-1 patients donate samples to power future discoveries
Knowledge-focused ENROLLING_BY_INVITATIONThis is a long-term follow-up banking protocol that collects medical information and tissue (blood, liver and lung) samples for future research; use of data and samples for research purposes is overseen by the Tissue Bank Advisory Committee; the purpose of the Bank is to further …
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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20,000 patients enrolled in pneumonia Fact-Finding mission
Knowledge-focused Recruiting nowThe main objective of this study is to investigate prevalence and risk factors for community-acquired pneumonia (CAP) and its interaction with comorbidities in an unselected group of adult patients receiving outpatient and inpatient care. In addition, information on HIV as a risk…
Sponsor: Capnetz Stiftung • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Breast vs. formula: which diet shapes baby brains best?
Knowledge-focused CompletedThe purpose of this study is to characterize physical growth, body composition, dietary intake, neurobehavioral development, and brain function of infants and children fed mostly breast-milk, milk-based formula or soy-based formula during their first year of life. Children are fo…
Sponsor: Arkansas Children's Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Study watches depressed moms and babies to understand development
Knowledge-focused CompletedThis study will examine 1) differences among mothers behaviors and how these behaviors influence their infants reactions, and 2) how mother-child interactions relate to children s temperament, and cognitive (thought processing) abilities, and other areas of development. Depresse…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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No treatment, just samples: new study aims to understand cancer immunity
Knowledge-focused Recruiting nowThis study will collect blood from patients with cancer to study the level of cells which decrease the immune response (suppressor cells) before and after chemotherapy. Patients 18 years of age and older with cancer may participate. This study does not involve treatment. Partici…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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Which feeding strategy works best for ventilator patients?
Knowledge-focused CompletedThe aim of this study is to compare two strategies of early enteral nutrition in terms of efficacy and complications in mechanically ventilated patients.
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Kidney donation may raise risk of scrotal surgery later in life
Knowledge-focused CompletedThis study will examine whether laparoscopic nephrectomy is associated with a higher long-term risk of receiving scrotal surgery in male living kidney donors compared to male nondonors from the general population who have similar baseline health indicators. Both groups will be fo…
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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96,000 adventists help uncover Diet-Cancer links
Knowledge-focused OngoingThe Adventist Health Study-2 is a long-term study, exploring the links between lifestyle, diet, and disease outcomes among Seventh-day Adventists. More than 96,000 church members from the U.S. and Canada are participating in the current study, AHS-2, conducted by researchers at t…
Sponsor: Loma Linda University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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NIH launches major lyme disease observation study to uncover hidden clues
Knowledge-focused Recruiting nowThis study is designed to establish a population of patients with Lyme disease for evaluation, treatment and follow-up to learn more about the infection. Patients with active Lyme disease may be eligible for this study. Participants will have a medical history and physical exam…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Radiation study seeks samples, not a cure
Knowledge-focused ENROLLING_BY_INVITATIONBackground: -Research in NCI's Radiation Oncology Branch depends on the availability of blood and urine samples from patients receiving radiation therapy. Objectives: -To explore the effects of radiation therapy on gene expression in white blood cells, to measure radiation dam…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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NIH launches major study to unlock secrets of rare bone diseases
Knowledge-focused Recruiting nowThis study has four objectives: 1) to provide investigators the opportunity to study bone specimens from patients with various skeletal diseases; 2) to treat patients with skeletal diseases at the NIH; 3) to expose NIH trainees to certain skeletal diseases; and 4) to gain more kn…
Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Short burst exercise safe for COPD lungs, small study finds
Knowledge-focused CompletedThe aim of the study is to observe the ventilatory and cardiac function (included the pulmonary arterial pressure) during an intermittent work exercise test with high density work load.
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Researchers launch registry to track rare endocrine tumors
Knowledge-focused OngoingObjectives: To contribute new and prospective data to our existing database library for patients with MEN1 and MEN2 at The University of Texas M.D. Anderson Cancer Center.
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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10,000 breast cancer patients donate tissue for science
Knowledge-focused Recruiting nowRATIONALE: Collecting and storing samples of tumor tissue from patients with breast cancer to study in the laboratory may help doctors learn more about cancer. PURPOSE: This phase I study is collecting tissue samples for future research from women undergoing surgery for breast c…
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Massive data hunt aims to unlock secrets of stem cell transplants
Knowledge-focused Recruiting nowTo provide the IRB approved mechanism for the prospective collection and analysis on participants who are undergoing either an autologous or allogeneic hematopoietic stem cell transplant for a disease in which a research question is not being addressed.
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Massive NIMH study seeks 16,000 volunteers to unlock secrets of mood and anxiety
Knowledge-focused Recruiting nowThe purpose of this protocol is to allow for the careful screening of patients and healthy volunteers for participation in research protocols in the Experimental Therapeutics and Pathophysiology Lab (ETPB) at the National Institute of Mental Health (NIMH) and for the collection o…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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German eye registry reveals shifting trends in corneal transplants
Knowledge-focused Recruiting nowAim of this study is to reflect on the changing trends in absolute numbers, surgical techniques and indications of corneal transplantations being performed in Germany. The Section Cornea of the German Ophthalmological Society provides interim-assessments on a regular basis about…
Sponsor: Universität des Saarlandes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Scientists seek tissue samples to unlock HIV and cancer mysteries
Knowledge-focused Recruiting nowBACKGROUND: * A number of important scientific advances can be made through the study of blood, bone marrow, tumor, or other tissue samples from patients with HIV infection, infection with Kaposi s sarcoma associated herpesvirus (KSHV), infection with other oncogenic viruses, or…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
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Big data reveals shifting patterns in rare cancer diagnosis
Knowledge-focused CompletedStage migration occurs when patients sound to have better survival or increased incidence rates at the early stage at diagnosis due to early detection of the disease. As carcinoid tumors are rare and there are no data supporting stage migration, the aim of this study was to perfo…
Sponsor: Suez Canal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC