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116076 trials found · Page 5618 of 5804
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Does loving money fuel gambling addiction? new study investigates
Knowledge-focused CompletedThe purpose of this study is to to explore the link between materialism and addiction to gambling and money
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Do Metal-Ceramic crowns harm your gums? Long-Term study investigates
Knowledge-focused CompletedThe goal of this clinical trial is to to evaluate the periodontal condition around metal-ceramic crown. The main question to be answered is: whether the metal-ceramic crown is the cause of gum changes? The study offers to involve patients who receive single metal-ceramic crown an…
Phase: NA • Sponsor: Riga Stradins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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New MRI technique aims to sharpen lung images
Knowledge-focused CompletedThis research study has 2 purposes: 1. To learn about new ways to use Magnetic Resonance Imaging (MRI) to take clearer pictures of the lungs. A type of MRI called Ultra Short Echo Time (UTE) will be used as well as traditional MRI. 2. To collect images and health information abo…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Glaucoma study reveals how quickly early cases worsen
Knowledge-focused CompletedThe purpose of this study is to measure how many patients develop worsening glaucoma in the early years (2-4 years) of routine monitoring in hospital eye services. We will study a group of patients who were initially diagnosed as having glaucoma, or having high pressure in the ey…
Sponsor: University of Aberdeen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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No new treatment, just Check-Ups: gene therapy patients monitored for 15 years
Knowledge-focused ENROLLING_BY_INVITATIONBackground: \- Gene therapy is a way to treat or prevent disease using genes. It is monitored very closely by regulators because there can be long-term, unexpected side effects. NIH is required to try to contact people who have been treated with gene therapy at least annually fo…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Massive study tracks 3,450 patients with aortic stenosis to uncover prognosis clues
Knowledge-focused Recruiting nowAortic stenosis is the most common valvulopathy in Western countries. Cardiac EchoDoppler is the reference method for assessment of aortic stenosis and provides prognostic elements. However, it is imperfect with many inconsistencies between measures. On the other hand, the progno…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Brain scans reveal how collective memory rewires individual recall
Knowledge-focused CompletedSchemas describe mental structures storing recurrent and organized pattern of information. Schemas may have a strong influence on the process of storing and retrieving new information into memory. Previous approaches in the cognitive neuroscience of memory have entirely focused o…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:02 UTC
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Rural health revolution: training future doctors and PAs to collaborate
Knowledge-focused CompletedThe interprofessional practice \& education curriculum for the students to be employed in this study will include five modalities in a scaffolded structure progressing from low- to high-fidelity experiences over a two-year period: (1) classroom didactic sessions; (2) simulation l…
Phase: NA • Sponsor: Pacific Northwest University of Health Sciences • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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MRI reveals how ACL grafts change shape after surgery
Knowledge-focused CompletedMRI study of ballooning and ligamentisation short transplants of anterior cruciate ligament (ACL) according to DT4 technique in 60 patients with more than one year of follow up.
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Eye-Opening study: pupil size may reveal pain levels
Knowledge-focused CompletedThe purpose of this research study is to test whether researchers can reliably measure the response pupils have when an acute painful stimulus is experienced. Changes in the size of the pupil of the eye can be an indicator of brain activity in a region of the brain that is import…
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New painkiller candidate MT-8554 tested in healthy men
Knowledge-focused CompletedThe purpose of this study is to investigate the pharmacodynamic effect of single doses of MT-8554 in healthy subjects.
Phase: PHASE1 • Sponsor: Tanabe Pharma Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Fluid before surgery may speed up bathroom breaks
Knowledge-focused CompletedThe primary aim of this study is to compare, in women undergoing tension-free vaginal tape (TVT) insertion under sedation and local anaesthetic infiltration, the time interval of first void following surgery between a group of patients who received intravenous fluids to those who…
Phase: NA • Sponsor: Gloucestershire Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Thirst-Guided hydration studied in Ultra-Trail runners
Knowledge-focused CompletedThe main objective of this study is to evaluate the impact of a hydration protocol "at thirst" compared to other "not at thirst" hydration protocols on the changes in serum sodium in runners of the Ultra Trail Mont-Blanc (UTMB) in 2015.
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New scans aim to spot aneurysm weak spots
Knowledge-focused Recruiting nowThe primary aim of this study is to establish the practicality of using two novel imaging modalities for the assessment of biomechanical properties of the aorta.
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:57 UTC
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Sensors track apathy in dementia patients
Knowledge-focused CompletedThe purpose of this study is to provide relevant quantitative evaluation of apathy close to real life situation by means of a multimodal sensor system integrated.
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Tiny study hopes to predict blood cancer risk from genetic mutations
Knowledge-focused TerminatedThe project's objective is to identify and characterize somatic mutations in cases of idiopathic cytopenia of undetermined significance (ICUS) on the basis of molecular defects found in myelodysplastic syndrome (MDS), in order to validate the hypothesis whereby ICUS may be a prec…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Blood marker may forecast recovery after colon surgery
Knowledge-focused CompletedColic and rectal resection represents a majority of hospitalizations in visceral surgery. The objective of this study was to evaluate the prognostic of inflammatory markers dosage (CRP, procalcitonin and venous lactate) on the postoperative recovery after colorectal surgery and o…
Phase: NA • Sponsor: Centre Hospitalier Departemental Vendee • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Tiny study probes muscle oxygen in rare nerve and muscle diseases
Knowledge-focused CompletedPrevious studies showed modifications of muscle oxygenation parameters in muscular dystrophies du to an impairment or an absence of dystrophin. Our study aim at assessing muscle oxygenation during effort in different neuromuscular diseases (muscular dystrophies related and not r…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Breath-Holding vs. exhaling: which pushing style is safer for delivery?
Knowledge-focused CompletedThe objective of this randomized clinical trial is to assess and compare the effectiveness of directed closed-glottis (Valsalva) pushing (pushing while holding one's breath) vs. directed open-glottis pushing (pushing during a prolonged exhalation) during the second stage of labor…
Phase: NA • Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New tool helps doctors talk better with cancer patients
Knowledge-focused CompletedValidation of the PO-BADO in its short and long versions that need a standardized validation process with the inclusion of 450 Patients
Sponsor: Institut Bergonié • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC