Simple steroid shot may stop Post-Surgery vomiting in women

NCT ID NCT07421817

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving a single dose of the steroid dexamethasone before laparoscopic gynecologic surgery reduces vomiting in the first 24 hours after the procedure. 120 women were randomly assigned to receive either dexamethasone or a placebo at the start of anesthesia. The main goal was to see how many women vomited after surgery, and the study also looked at nausea severity and the need for additional anti-nausea medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Dexamethasone (a corticosteroid drug given as a single intravenous dose)
What this could lead to
If effective, this could provide a simple, low-cost way to prevent vomiting after laparoscopic gynecologic surgery.
What could go wrong
This is a small, completed trial with 120 participants, so results may not apply to all patients. Dexamethasone can have side effects like increased blood sugar or infection risk.

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Conditions

The condition(s) this trial relates to.

Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Gynecology and Obstetrics, Al-Nafees Medical College and Hospital-Isra University

    Islamabad, ICT, 44000, Pakistan

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