Could a common sedative stop post-surgery nausea?
NCT ID NCT07668700
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding a low dose of midazolam (a sedative) to the usual two-drug combination (dexamethasone and ondansetron) could better prevent nausea and vomiting after gynecologic laparoscopic surgery. 300 women aged 19–65 took part. Half received the standard two drugs plus a placebo, and the other half received the standard two drugs plus midazolam. The main goal was to see if fewer patients had significant nausea (score under 4 on a 0–10 scale) in the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
midazolam
What this could lead to
If it works, this could offer a better way to prevent nausea and vomiting after surgery, improving patient comfort and recovery.
What could go wrong
This is a small, single-center Phase 2 trial. The benefit may be modest, and midazolam can cause drowsiness or other side effects.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Anaesthesiology
Lahore, Punjab Province, 54590, Pakistan