Could a common sedative stop post-surgery nausea?
NCT ID NCT07668700
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding a low dose of midazolam (a sedative) to the usual two-drug combination (dexamethasone and ondansetron) could better prevent nausea and vomiting after gynecologic laparoscopic surgery. 300 women aged 19–65 took part. Half received the standard two drugs plus a placebo, and the other half received the standard two drugs plus midazolam. The main goal was to see if fewer patients had significant nausea (score under 4 on a 0–10 scale) in the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- midazolam
- What this could lead to
- If it works, this could offer a better way to prevent nausea and vomiting after surgery, improving patient comfort and recovery.
- What could go wrong
- This is a small, single-center Phase 2 trial. The benefit may be modest, and midazolam can cause drowsiness or other side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Anaesthesiology
Lahore, Punjab Province, 54590, Pakistan
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Other studies related to the condition(s) this trial covers.
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